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Record W4407948655 · doi:10.1109/jerm.2025.3537462

Principal Component Regression for Broadband Microwave-Microfluidic Chemometrics on Small Sample Counts

2025· article· en· W4407948655 on OpenAlexaff
Marie Mertens, Raphaël Trouillon, Tomislav Marković, Ke Wu, Dominique Schreurs

Bibliographic record

VenueIEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology · 2025
Typearticle
Languageen
FieldEngineering
TopicMicrowave and Dielectric Measurement Techniques
Canadian institutionsPolytechnique Montréal
FundersKU LeuvenFonds Wetenschappelijk Onderzoek
KeywordsChemometricsPrincipal component regressionPrincipal component analysisBroadbandComponent (thermodynamics)Sample (material)MicrofluidicsStatisticsMaterials scienceComputer scienceMathematicsChromatographyTelecommunicationsChemistryNanotechnologyPhysics

Abstract

fetched live from OpenAlex

While broadband dielectric spectroscopy enables label-free analysis of biological and chemical materials, extracting multiple concentrations from the data has remained a challenge. This work is one of the first demonstrations of simultaneous concentration extraction of three liquid constituents in a solution using broadband microwave spectroscopic data. Furthermore, the used methods eliminate the need for de-embedding or characterizing the measurement setup, simplifying the process. Advanced regression techniques such as Principal Component Regression (PCR) and Principal Least Squares (PLS) are applied to determine the concentrations of sodium chloride, glucose, and ethanol in water. As input data, <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex-math notation="LaTeX">$S$</tex-math></inline-formula>-parameters are measured between 0.5 and 26.5 GHz on a broadband coplanar waveguide sensor with a microfluidic container to transport the liquids. The training datasets consist of 27 and 34 samples, respectively. The mean absolute percentage error for sodium chloride predictions ranged from 3-5% for the different methods, while the minimal errors for glucose and ethanol predictions were 6-7% and 4-6%, respectively.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.130
Threshold uncertainty score0.456

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.043
GPT teacher head0.303
Teacher spread0.260 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2025
Admission routes1
Has abstractyes

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Same venueIEEE Journal of Electromagnetics RF and Microwaves in Medicine and BiologySame topicMicrowave and Dielectric Measurement TechniquesFrench-language works237,207