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Record W4407952220 · doi:10.1371/journal.pmen.0000253

A tutorial on the what, why, and how of Bayesian analysis: Estimating mood and anxiety disorder prevalence using a Canadian data linkage study

2025· article· en· W4407952220 on OpenAlexafffundabout
Myanca Rodrigues, Jordan Edwards, Tea Rosic, Jhalok Ronjan Talukdar, Saifur Rahman Chowdhury, Sameer Parpia, Glenda Babe, Claire de Oliveira, Zainab Samaan, Lehana Thabane

Bibliographic record

VenuePLOS mental health. · 2025
Typearticle
Languageen
FieldPsychology
TopicMental Health Research Topics
Canadian institutionsUniversity of TorontoCentre for Addiction and Mental HealthUniversity of OttawaQueen's UniversityMcMaster UniversitySt. Joseph’s Healthcare HamiltonChildren's Hospital of Eastern OntarioImpact
FundersInstitute of Neurosciences, Mental Health and AddictionMcMaster University
KeywordsAnxietyMoodLinkage (software)PsychologyClinical psychologyBayesian probabilityGeneralized anxiety disorderPsychiatryComputer scienceArtificial intelligenceGeneticsBiology

Abstract

fetched live from OpenAlex

Bayesian analyses offer a robust framework for integrating data from multiple sources to better inform population-level estimates of disease prevalence. This methodological approach is particularly suited to instances where data from observational studies is linked to administrative health records, with the capacity to advance our understanding of psychiatric disorders. The objective of our paper was to provide an introductory overview and tutorial on Bayesian analysis for primary observational studies in mental health research. We provided: (i) an overview of Bayesian statistics, (ii) the utility of Bayesian methods for psychiatric epidemiology, (iii) a tutorial example of a Bayesian approach to estimating the prevalence of mood and/or anxiety disorders in observational research, and (iv) suggestions for reporting Bayesian analyses in health research.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.011
metaresearch head score (Gemma)0.030
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.459
Threshold uncertainty score0.923

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0110.030
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.002
Bibliometrics0.0040.005
Science and technology studies0.0020.002
Scholarly communication0.0030.002
Open science0.0020.002
Research integrity0.0020.003
Insufficient payload (model declined to judge)0.0260.006

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.106
GPT teacher head0.433
Teacher spread0.327 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes3
Has abstractyes

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