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Record W4407961658 · doi:10.1139/apnm-2024-0390

Effects of eccentric versus stretching exercise training on cognitive function of older women

2025· article· en· W4407961658 on OpenAlexvenueno aff
Min-Jyue Huang, Favil Singh, Dennis R. Taaffe, Trevor C. Chen, Kazunori Nosaka

Bibliographic record

VenueApplied Physiology Nutrition and Metabolism · 2025
Typearticle
Languageen
FieldHealth Professions
TopicTherapeutic Uses of Natural Elements
Canadian institutionsnot available
Fundersnot available
KeywordsEccentric trainingEccentricMemory spanMedicineStroop effectCognitionTrail Making TestPhysical therapyPhysical medicine and rehabilitationPsychologyInternal medicineWorking memoryCognitive impairment

Abstract

fetched live from OpenAlex

Exercises focusing on eccentric contractions may stimulate the brain better, improving cognitive function. We tested the hypothesis that executive function and attention would improve more after eccentric resistance exercise (ECC) than stretching exercise (STRETCH) training. Healthy older women (65–75 years) underwent either ECC ( n = 14) or STRETCH ( n = 14) intervention for 8 weeks. ECC consisted of seven exercises emphasizing eccentric contractions while STRETCH performed 12 stretching exercises, with supervised sessions undertaken twice weekly accompanied by a home-based program. Executive function and attention were assessed using the Stroop test of color naming (STCN) and conflicting color words, symbol digit modalities test, digit span test (DST), and trail making tests (TMT-A and TMT-B), and six physical function tests were undertaken before and after the 8-week training period. Fasting blood samples were obtained before and after the training. A significant ( p < 0.05) group × time interaction effect was evident for STCN, DST, and TMT-A, with only ECC showing improvements (DST:14.7 ± 27% and TMT-A:10.2 ± 12%) from pre- to post-training. No significant changes in other cognitive function tests were found for either group. All physical function tests except one-leg balance test showed greater improvement ( p < 0.05) for ECC than STRETCH. No significant changes in blood lipid profile and brain-derived neurotrophic factor were found, but serum glucose concentration and glycosylated hemoglobin decreased ( p < 0.05) in ECC. These results suggest that a short-term body-weight eccentric exercise intervention was effective in enhancing components of cognitive and physical function of older women and may prove a useful strategy in combating age-related decline in cognitive and physical function.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.754
Threshold uncertainty score0.508

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.026
GPT teacher head0.348
Teacher spread0.322 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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