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Record W4407976027 · doi:10.1136/bmjph-2024-001590

Childhood socioeconomic position and healthy ageing: results from five harmonised cohort studies in the ATHLOS consortium

2025· article· en· W4407976027 on OpenAlexaff
Yu‐Tzu Wu, Sam Gnanapragasam, Albert Sánchez‐Niubò, Muhammad Zakir Hossin, Ilona Grünberger, Seppo Koskinen, Rachel Cooper, Matthew Prina

Bibliographic record

VenueBMJ Public Health · 2025
Typearticle
Languageen
FieldSocial Sciences
TopicHealth disparities and outcomes
Canadian institutionsUniversity of British Columbia
FundersMedical Research CouncilNational Institutes of HealthHorizon 2020 Framework ProgrammePeking UniversityNational Institute on AgingForskningsrådet om Hälsa, Arbetsliv och VälfärdTerveyden ja hyvinvoinnin laitosVetenskapsrådetNational Natural Science Foundation of ChinaEconomic and Social Research CouncilWorld Health OrganizationEuropean CommissionUniversity of East AngliaNational Institute for Health and Care ResearchWellcome TrustUniversity College LondonUniwersytet Jagielloński Collegium MedicumWorld Bank GroupJohn D. and Catherine T. MacArthur Foundation
KeywordsSocioeconomic statusMediationDisadvantageAgeingCohortEducational attainmentEarly childhoodLife course approachCohort studyGerontologyLongitudinal studyDemographyPsychologyMedicineDevelopmental psychologyEnvironmental healthPopulationPolitical scienceSociology

Abstract

fetched live from OpenAlex

Introduction: Childhood socioeconomic position (SEP) has been identified as a key determinant of health. However, earlier literature is largely from high-income countries and provides limited evidence on the prolonging impacts of childhood disadvantage on healthy ageing across diverse settings and populations. The aim of this study is to investigate the associations between childhood SEP and healthy ageing across multiple countries and the mediation effects of adult SEP, individual education and wealth, on these associations. Methods: Using the harmonised dataset of five cohort studies in the Ageing Trajectories of Health-Longitudinal Opportunities and Synergies (ATHLOS) project, this study was based on 57 956 people aged ≥50 years (women: 53.3%) living in China, Finland, UK, Poland, South Africa and Mexico. The associations between childhood SEP (parental education and occupation) and healthy ageing scores were examined using linear regression modelling. Causal mediation analysis was carried out to estimate the percentage of indirect effects via adult SEP (individual education and wealth). Results: Higher levels of childhood SEP were associated with higher healthy ageing scores by up to five points and similar patterns were observed across populations from different countries. The associations were mediated by adult SEP and the range of mediation effects was between 21% and 78%. Conclusions: This study found childhood SEP was associated with poor health in later life across high-income, middle-income and low-income countries. Addressing socioeconomic disadvantage, such as improving education attainment, may moderate the impacts of adversity in early life and support health and functioning in later life.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.007
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesScience and technology studies
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.532
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0070.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.086
GPT teacher head0.421
Teacher spread0.335 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2025
Admission routes1
Has abstractyes

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