Synergistic effect of Majoon-e-Suranjaan and isometric exercises in improving rheumatoid arthritis
Bibliographic record
Abstract
Objective: The study aimed to evaluate the synergistic effects of Majoon-e-Suranjaan with and without isometric exercises in patients with rheumatoid arthritis (RA).Methods: A prospective, pragmatic, community based, parallel group, single blinded randomized controlled trial conducted at Muhammad Physical Therapy and Rehabilitation Clinic and Rehabilitation Centre, Multan, from May to October 2023.The trial was approved and registered in the Iranian Registry of Clinical Trials (IRCT20230202057310N5).Ninety-five patients were randomly assigned to two groups.Group A received Majoon-e-Suranjaan (5 g orally, twice daily).Group B received the same dosage of Majoon-e-Suranjaan along with The isometric exercises.The exercise protocol for group B consisted of three weekly sessions, each lasting 40 minutes.Patients were evaluated at baseline and at the 24 th week based on serological markers, including rheumatoid factor (RF), erythrocyte sedimentation rate (ESR), disease activity score (DAS), and C-reactive protein (CRP), as well as X-ray findings such as nodules and bone degeneration in affected joints.Pain, morning stiffness, and functional activities were assessed using the Western Ontario and McMaster Universities Arthritis Index (WOMAC) and the Numerical Pain Rating Scale (NPRS).Results: Of the 95 patients randomized, 90 completed the 24-week treatment.Among them, 60 (66.6%) were female, and 30 (33.3%) were male.Group B showed significantly greater improvements compared to Group A in in WOMAC activities of daily living (P=0.001),WOMAC stiffness (P=0.004),WOMAC pain and DAS (P=0.000),NPRS (P=0.001).Additionally, Group B demonstrated significant improvements in RF (P=0.001),ESR (P=0.002), and CRP (P=0.003)compared to group A. Conclusions: This study demonstrated the synergistic effect of Majoon-e-Suranjaan and isometric exercises in RA patients, highlighting the potential for more effective RA treatment strategies.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.003 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".