Top stories on diagnosis and management of immune-mediated congenital complete atrioventricular block in utero
Bibliographic record
Abstract
Complete atrioventricular block (CAVB) is a disease of the developing fetus that mainly results from the transplacental transfer of high-titer maternal anti-Ro/SSA autoantibodies.About 2%-4% of antibody-exposed fetuses have manifestations of cardiac neonatal lupus (CNL), such as AV block (AVB), carditis, and endocardial fibroelastosis (EFE).CAVB, the most common CNL manifestation, carries significant mortality and morbidity risks, with most deaths occurring perinatally and >70% of survivors requiring permanent pacing beginning during infancy.Current practice guidelines including by the Society for Maternal-Fetal Medicine advise against the prenatal surveillance of antibodyexposed fetuses and against steroid treatment of fetal AVB because of their "unproven benefit." 1 The latest research findings, however, endorse a more preemptive surveillance and treatment approach for CNL with the potential of life-altering and life-saving consequences for affected children.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".