Comparison of intra-articular steroid injection with combined oral steroid and intra-articular steroid injection to treat patients with knee osteoarthritis
Bibliographic record
Abstract
Objective: To evaluate the benefits provided by a short course of low dose oral Prednisolone followed by intra-articular injection of Methylprednisolone to treat osteoarthritis Knee as compared to intra-articular injection of Methylprednisolone and placebo. Study Design: Quasi-experimental study Place and Duration of Study: Department of Rehabilitation Medicine, Combined Military Hospital Quetta, Pakistan from Aug to Nov 2023. Methodology: Ninety nine patients with OA of Knee joint were randomly assigned to 3 groups, Group-A received a short course (14 days) of low dose oral steroids (15 mg Prednisolone ) followed by one intra-articular steroid injection (administered two weeks later). Patients in Group-B received intra-articular injection of steroid only and Group-C received intra-articular injection of normal saline. All patients were evaluated using the Western Ontario and McMaster Universities (WOMAC) & Visual Analogue Scale (VAS) score before the treatment and at 2,6,12 and 16 weeks following treatment. Result: There were significant improvements in both Group-A & Group-B. Particularly, patients in Group-A had significantly superior VAS and WOMAC scores than were seen in groups B and C. The VAS and WOMAC scores remained the same as were pre-treatment in group C. Group-A and B both showed improvement but to different extent with superior results in Group-A till 16 weeks. Conclusion: The combination of short course of low dose oral steroids with intra-articular steroid injections resulted in significantly superior symptomatic improvement, with sustained lower VAS and WOMAC scores, hence improving quality of life for 16 weeks.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".