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Record W4408033317 · doi:10.3390/children12030306

Mechanical Circulatory Support in Congenital Heart Disease

2025· review· en· W4408033317 on OpenAlexaff
Áine Lynch, Aamir Jeewa

Bibliographic record

VenueChildren · 2025
Typereview
Languageen
FieldEngineering
TopicMechanical Circulatory Support Devices
Canadian institutionsHospital for Sick Children
Fundersnot available
KeywordsHeart failureMedicineHeart diseasePsychosocialReferralCirculatory systemDiseaseIntensive care medicineHeart transplantationInternal medicineCardiologyNursing

Abstract

fetched live from OpenAlex

As early survival outcomes have improved, heart failure in children with congenital heart disease (CHD) has become a growing problem. Primary care providers and pediatricians are thus encountering increasing numbers of children with or at-risk for heart failure. Despite medication, many of these children progress to end-stage heart failure and require heart transplant for long-term survival. Mechanical circulatory support (MCS) is increasingly utilized to support this cohort both acutely when recovery is anticipated, and as a bridge to transplant. Early referral to tertiary heart failure and MCS teams is key to facilitate timely institution of MCS and preserve end-organ function. MCS in children with CHD presents unique challenges due to patient size and complex intra- and extra-cardiac anatomy. Evaluations for MCS should take into account patient size, anatomy, end-organ function, and psychosocial supports. The form of MCS utilized is dependent on clinical urgency, patient size, and anatomy. We describe the evolving landscape of MCS in pediatric patients with CHD.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.957
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.019
GPT teacher head0.268
Teacher spread0.249 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes1
Has abstractyes

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