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Record W4408082141 · doi:10.1186/s43166-025-00310-y

Cognitive frailty and falls among Egyptian older adults with rheumatoid arthritis

2025· article· en· W4408082141 on OpenAlexaboutno aff
Rahma A. Elziaty, Radwa M. Salah, Salma A. Khalil

Bibliographic record

VenueEgyptian Rheumatology and Rehabilitation · 2025
Typearticle
Languageen
FieldMedicine
TopicLong-Term Effects of COVID-19
Canadian institutionsnot available
Fundersnot available
KeywordsCognitionRheumatoid arthritisMedicineGerontologyOlder peoplePhysical medicine and rehabilitationPhysical therapyPsychiatryInternal medicine

Abstract

fetched live from OpenAlex

Abstract Background Cognitive frailty is defined through a combination of physical frailty and cognitive impairment and is a growing concern in rheumatology. Rheumatoid arthritis is a lifelong disease, and the disease itself and the side effects of drug treatments may cause frailty. This study assessed the prevalence and risk factors for cognitive frailty and falls in people with rheumatoid arthritis. Results A cross-sectional study involving 105 rheumatoid arthritis patients (aged 60 and older) was performed. Each participant received a comprehensive medical history review. The Simplified Disease Activity Index (SDAI), the Montreal Cognitive Assessment, and the Frail Scale were assessed. Sixty-one patients (58.1%) exhibited mild cognitive impairment. Forty-eight (45.7%) were categorized as frail. Among the frail patients, 41 (85.4%) showed mild cognitive impairment. Cognitive frailty was observed in 41 patients (39%). Compared to prefrail patients, frail patients were older (mean age 68.98 ± 4.01 vs 63.54 ± 2.63; p < 0.0001), had a longer disease duration (33.00 ± 6.05 vs 26.77 ± 5.29; p < 0.0001), displayed higher disease activity (median SDAI 24 vs 10; p < 0.0001), and experienced a greater number of falls (2 vs 0; p < 0.0001). Conclusion Cognitive frailty is prevalent in RA patients. Age, level of education, disease duration, and disease severity are significant risk factors for frailty and cognitive impairment. RA patients who are frail are more prone to falls and therefore have a higher incidence of morbidity and adverse events.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.025
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.003
GPT teacher head0.254
Teacher spread0.251 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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