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Record W4408088887 · doi:10.1016/j.jad.2025.02.113

Associations between self-reported ADHD symptoms and depression and anxiety in mothers and fathers during the postpartum period: A Canadian nationwide longitudinal study

2025· article· en· W4408088887 on OpenAlexafffundabout
Dylan Johnson, Mark Wade, Flavia Marini, Simone N. Vigod, Hilary K. Brown, Sophie Grigoriadis, Rahman Shiri, Cindy‐Lee Dennis

Bibliographic record

VenueJournal of Affective Disorders · 2025
Typearticle
Languageen
FieldMedicine
TopicAttention Deficit Hyperactivity Disorder
Canadian institutionsSunnybrook Health Science CentreSunnybrook HospitalLunenfeld-Tanenbaum Research InstitutePublic Health OntarioWomen's College HospitalUniversity of Toronto
FundersCanadian Institutes of Health Research
KeywordsComorbidityAnxietyDepression (economics)Odds ratioPsychiatryPostpartum periodMedicineAttention deficit hyperactivity disorderOddsPostpartum depressionPsychologyPregnancyInternal medicineLogistic regression

Abstract

fetched live from OpenAlex

Attention-deficit hyperactivity disorder (ADHD) may be a risk factor for intra- and inter-parental affective disorders in the perinatal period, placing families at risk for negative outcomes. A large prospective cohort of Canadian women and their male partners ( N = 2544 couples) were recruited in the postpartum period. Repeated measures data were collected at baseline and six timepoints over 24-months postpartum. Self-reported ADHD symptoms were measured at baseline, and depression/anxiety were measured at all timepoints. Generalized estimating equations examined associations between possible ADHD and ADHD symptoms with new depression, anxiety, and comorbidity. Cross-parental associations were explored. Compared to mothers without, those with possible ADHD had higher odds of depression (adjusted odds ratio [aOR] = 1.70, 95 % CI [1.13–2.56]), anxiety (aOR = 1.74 [1.30–2.34]), and comorbidity (aOR = 1.66, [1.06–2.60]), at 3–24 months postpartum. Maternal ADHD symptoms were associated with anxiety in fathers (aOR = 1.03 [1.01–1.06] for 1-unit increase in symptoms) at 3–24-months. When compared to fathers without, those with possible ADHD had higher odds of depression (aOR = 2.33 [1.78–3.05]), anxiety (aOR = 2.02, [1.60–2.55]), and comorbidity (aOR = 2.05, [1.51–2.79]), as well as paternal ADHD symptoms associated with depression (aOR = 1.05, [1.01–1.08] for 1-unit increase in symptoms) and comorbidity (aOR = 1.04 [1.00–1.08] for 1-unit increase in symptoms) in mothers at 3–24-months. Self-reported measures. Parental ADHD in the postpartum period is associated with depression and anxiety among mothers and fathers. Paternal ADHD was a risk for maternal mental health problems in the early postpartum period, and maternal ADHD was a risk for paternal mental health problems in the late postpartum period. • Longitudinal data examined associations between parental ADHD and postpartum affective disorders. • Depression rates ranged from 7.2 to 8.6 % for fathers and 4.7–7.2 % for mothers from 3 to 24 months postpartum. • Anxiety rates ranged from 15.6 to 16.7 % for fathers and 18.5–19.2 % for mothers from 3 to 24 months postpartum. • Maternal ADHD was associated with maternal anxiety and depression, as well as paternal anxiety. • Paternal ADHD was associated with paternal anxiety and depression, as well as maternal depression.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.016
Threshold uncertainty score0.075

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.003
Science and technology studies0.0030.000
Scholarly communication0.0010.000
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.306
Teacher spread0.292 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes3
Has abstractyes

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