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MXenes as emerging materials to repair electroactive tissues and organs

2025· review· en· W4408098214 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueBioactive Materials · 2025
Typereview
Languageen
FieldMaterials Science
TopicMXene and MAX Phase Materials
Canadian institutionsSt. Boniface Hospital
FundersNational Society of Collegiate ScholarsH2020 Marie Skłodowska-Curie ActionsNatural Sciences and Engineering Research Council of CanadaCanadian Institutes of Health Research
KeywordsMXenesMaterials scienceBiomedical engineeringNanotechnologyMedicine

Abstract

fetched live from OpenAlex

Nanomaterials with electroactive properties have taken a big leap for tissue repair and regeneration due to their unique physiochemical properties and biocompatibility. MXenes, an emerging class of electroactive materials have generated considerable interest for their biomedical applications from bench to bedside. Recently, the application of these two-dimensional wonder materials have been extensively investigated in the areas of biosensors, bioimaging and repair of electroactive organs, owing to their outstanding electromechanical properties, photothermal capabilities, hydrophilicity, and flexibility. The currently available data reports that there is significant potential to employ MXene nanomaterials for repair, regeneration and functioning of electroactive tissues and organs such as brain, spinal cord, heart, bone, skeletal muscle and skin. The current review is the first report that compiles the most recent advances in the application of MXenes in bioelectronics and the development of biomimetic scaffolds for repair, regeneration and functioning of electroactive tissues and organs including heart, nervous system, skin, bone and skeletal muscle. The content in this article focuses on unique features of MXenes, synthesis process, with emphasis on MXene-based electroactive tissue engineering constructs, biosensors and wearable biointerfaces. Additionally, a section on the future of MXenes is presented with a focus on the clinical applications of MXenes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.449
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.001
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0050.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0010.001
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0080.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.027
GPT teacher head0.357
Teacher spread0.330 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it