Human amniotic membrane graft with viscodissection and intraoperative OCT for macular hole repair
Bibliographic record
Abstract
Objective: To present the human amniotic membrane (hAM) graft with the novel addition of viscodissection and usage of intraoperative OCT as a potential approach to treating challenging macular holes and to describe the outcomes. Design: Retrospective interventional case series. Participants: 10 patients with large, chronic, or persistent macular holes were included in this study. Methods: 10 eyes of 10 patients were treated using a hAM graft with viscodissection. Intraoperative OCT was utilized to assist the placement of the graft. Outcomes were monitored through clinical examinations, retinal imaging, and OCT. Results: Macular holes were closed in all 10 patients and remained so during the entirety of the follow-up periods. 9 out of 10 patients experienced an improvement in visual acuity. Mean best corrected visual acuity increased from 1.68 logMAR (20/1000) preoperative to 0.74 logMAR (20/100) at 6 months postoperative. No adverse events were observed for any of our patients. Conclusions: The addition of viscodissection to the standard hAM graft surgery is a potential optimization that reduces risks of iatrogenic damage to the retina. Surgeons can consider including this approach as part of their arsenal to treat such macular holes.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".