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Record W4408203725 · doi:10.1051/bioconf/202516301004

Graph-based method for constructing consensus trees

2025· article· en· W4408203725 on OpenAlex
Elio Torquet, Jesper Jansson, Nadia Tahiri

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueBIO Web of Conferences · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicBioinformatics and Genomic Networks
Canadian institutionsUniversité de Sherbrooke
FundersNatural Sciences and Engineering Research Council of CanadaUniversité de Sherbrooke
KeywordsComputer scienceGraphTheoretical computer science

Abstract

fetched live from OpenAlex

A consensus tree is a phylogenetic tree that synthesizes a given collection of phylogenetic trees, all of which share the same leaf labels but may have different topologies, typically obtained through bootstrapping. Our research focuses on creating a consensus tree from a collection of phylogenetic trees, each detailed with branch-length data. We integrate branch lengths into the consensus to encapsulate the progression rate of genetic mutations. However, traditional consensus trees, such as the strict consensus tree, primarily focus on the topological structure of these trees, often neglecting the informative value of branch lengths. This oversight disregards a crucial aspect of evolutionary study and highlights a notable gap in traditional phylogenetic approaches. In this paper, we extend PrimConsTree , an graph-based method for constructing consensus trees. This algorithm incorporates topological information, edge frequency, clade frequency, and branch length to construct a more robust and comprehensive consensus tree. Our adaptation of the well-known Prim algorithm efficiently identifies the maximum frequency branch and maximum frequency nodes to build the optimal consensus tree. This strategy was pre-processed with clustering steps to calibrate the robustness and accuracy of the consensus tree. Availability and implementation: The source code of PrimConsTree is freely available on GitHub at https://github.com/tahiri-lab/PrimConsTree .

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.586
Threshold uncertainty score0.367

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.285
Teacher spread0.269 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it