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Record W4408207919 · doi:10.52783/jns.v14.1876

Maternal and neonatal complications of trial of labor after two cesarean sections (TOLAC-2) compared with repeat cesarean section (RCS-2): Systematic review and meta-analysis

2025· article· en· W4408207919 on OpenAlexaboutno aff
J. M. Ramírez-Morey, O. E Ramírez Llerena, Arul King J

Bibliographic record

VenueJournal of Neonatal Surgery · 2025
Typearticle
Languageen
FieldMedicine
TopicMaternal and Perinatal Health Interventions
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineMeta-analysisSection (typography)ObstetricsInternal medicine

Abstract

fetched live from OpenAlex

Title: Maternal and neonatal complications of the trial of labour after two caesarean sections (PPDC-2) versus repeat caesarean section (CR-2): Systematic review and meta-analysis. Background: PPDC-2 is a behavior that is not accepted in all latitudes. Women who want natural childbirth do not receive the opportunity. The objective wasto conduct a systematic review and meta-analysis on the maternal and neonatal complications of PPDC-2 versus CR-2. Methods: The eligibility criteria were: pregnant women of ≥22 weeks, two cesarean sections, cephalic presentation, no contraindications to natural delivery, no fetal malformations who undergo PPDC-2. We searched the libraries PubMed, Scopus, Embase and other websites of organisations linked to Obstetrics and Gynaecology. We assessed risk of bias using the Newcastle-Ottawa Scale. The Synthetic Method was used to summarize and present the results. Results: The number of included articles that met the eligibility criteria was 10, with 3316 participants in the intervention group (PPDC-2) and 54054 in the control group (CR-2). The studies were cohort studies. The average success rate of PPDC-2 was 62.1%. There were no differences in maternal and neonatal complications in most publications. The rate of uterine rupture was very small. Discussion: The information comes from good quality cohort studies (level of evidence 2b). PPDC-2 is a reasonable and relatively safe option, comparable to CR-2. Others: It was financed with own resources, no protocol was carried out and it was not recorded on the basis of systematic reviews.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.654
Threshold uncertainty score0.510

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.043
GPT teacher head0.337
Teacher spread0.295 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designMeta-analysis
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

Explore more

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