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Record W4408221165 · doi:10.1016/j.jaccas.2024.103071

Relevance of Pressure Recovery in a Young Patient With Aortic Stenosis and Small-Caliber Aorta

2025· article· en· W4408221165 on OpenAlexaboutno aff
Jan‐Christian Reil, Hazem Omran, Nael Hasan, Gert‐Hinrich Reil, Lech Paluszkiewicz

Bibliographic record

VenueJACC Case Reports · 2025
Typearticle
Languageen
FieldMedicine
TopicCardiac Valve Diseases and Treatments
Canadian institutionsnot available
Fundersnot available
KeywordsCaliberStenosisMedicineCardiologyAortaInternal medicineRelevance (law)Clinical significanceRadiologyMaterials sciencePolitical scienceMetallurgy

Abstract

fetched live from OpenAlex

The case concerns a 20-year-old patient with Canadian Cardiovascular Society class II angina who was initially referred for aortic valve replacement because of a suspected high-grade aortic valve stenosis with increased transvalvular gradients (max/mean: 70/40 mm Hg) measured by Doppler echocardiography. Examinations using transesophageal echocardiography and computed tomography showed a sufficiently opening bicuspid aortic valve, excluded supra- and subvalvular stenoses, and measured a narrow aorta (diameter: 2 cm). The explanation for the highly increased gradients across the aortic valve was the pressure recovery (PR) phenomenon, which cannot be detected by Doppler gradients. Distal to a stenosis kinetic energy is converted back into potential energy, most effectively in small aortas (area: <3 cm 2 ). This reduces the actual transvalvular pressure gradient, which can directly be determined with cardiac catheterization. Accordingly, invasive measurements showed a moderate aortic stenosis (mean transvalvular pressure: 19 mm Hg), almost identical to the PR-corrected Doppler measurements. A high-grade stenosis of the proximal left anterior descending artery was treated interventionally, which could explain the angina symptoms.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.044
Threshold uncertainty score0.393

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.280
Teacher spread0.272 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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