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Record W4408245021 · doi:10.1089/end.2024.0667

Fluoroless Ureteroscopy Under Local Anesthetic Gel: Experience from a Canadian Tertiary Referral Center

2025· article· en· W4408245021 on OpenAlexaffabout
Tarek Benzouak, Ahmad Alshammari, Abdulmalik Addar, Fadl Hamouche, Abdullah Alahmari„, Sébastien Belliveau, Michael F. Maalouf, Rakan Al-Haidey, Sero Andonian, Nada Mohamed, Anne Yin, Nader Fahmy

Bibliographic record

VenueJournal of Endourology · 2025
Typearticle
Languageen
FieldMedicine
TopicKidney Stones and Urolithiasis Treatments
Canadian institutionsMcGill UniversityUniversité de MontréalMcGill University Health Centre
Fundersnot available
KeywordsMedicineUreteroscopyVisual analogue scaleProspective cohort studyLower urinary tract symptomsLidocaineLocal anestheticTertiary careGold standard (test)Urinary systemSurgeryUreterInternal medicineCancerProstate

Abstract

fetched live from OpenAlex

Introduction: Flexible ureteroscopy (URS) is the backbone of diagnosing upper urinary tract pathologies. Recent advancements in scope design have led to smaller, more maneuverable scopes with enhanced precision. The aim of this study was to assess feasibility of fluoroless URS under a local anesthetic (LA) gel. Patients and Methods: A prospective cohort study was performed at a Canadian tertiary care center. All patients booked for a diagnostic URS were included in this study. All patients were given intraurethral local lidocaine gel and instructed to signal if discomfort was encountered. Data collected include age, gender, indications of URS, history of URS, ureteral stenting, comorbidity index, and the use of a guidewire, as well as pain using a visual analog scale. Results: A total of 61 URSs using LA were performed on 38 patients. The majority of patients were men (68.9%). Indications for URS were to rule out upper tract urothelial cancer (47.5%), stricture (32.8%), or urolithiasis (19.7%). The average pain score, as rated by the visual analog scale, was 2.05 (standard deviation = 2.037). Only one patient did not want to continue his URS under LA. Guidewire use was associated with an average increase of 1.87 in pain score when compared with freehand URS (β = 1.869, standard error [SE] = 0.610, t = 3.063, p = 0.004, r partial = 0.398). Male patients reported a 1.38 decrease in pain scores compared with female patients (β = −1.380, SE = 0.615, t = −2.244, p = 0.029, r partial = −0.302). Conclusions: LA URS was well tolerated in our patient population. Randomized controlled trials on URS with LA vs general or spinal anesthesia are needed to broaden its use, increase accessibility, and improve health care resource utilization.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.040
Threshold uncertainty score0.981

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.299
Teacher spread0.286 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes2
Has abstractyes

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