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Record W4408246064 · doi:10.1093/eurjpc/zwaf119

Identification and management of cardiopulmonary risk in patients with chronic obstructive pulmonary disease: a multidisciplinary consensus and modified Delphi study

2025· article· en· W4408246064 on OpenAlexaff
Chris P Gale, John R. Hurst, Nathaniel M. Hawkins, Jean Bourbeau, MeiLan K. Han, Carolyn Lam, Darcy D. Marciniuk, David A. Price, Daiana Stolz, Ty J. Gluckman, Shelley Zieroth, Ramesh Nadarajah, Robert P. Young, Dave Singh, Fernando J. Martínez, David D. Berg, Mohit Bhutani, Amr Abdin, Dzifa Ahadzi, Albert B. Albay, Bernardino Alcázar Navarrete, Luís Alves, Sameera Ansari, Antonio Anzueto, Felix Barasa, Giuseppe Biondi‐Zoccai, Raffaele Bugiardini, Daniela Calderaro, Arturo Cortés-Telles, Michael G. Crooks, Diego Echazarreta, Nabil Farag, Frits M.E. Franssen, Suzanne Fredericks, C P Gale, Olga Milena García Morales, Melissa Gaviria, Bariş Gencer, Gonzalo Gianella, Kari Hanne Gjeilo, Martha Gulati, MeiLan K Han, Jeroen Hendriks, Anh-Thu Huynh Dang, Majdy Idrees, Tobin Joseph, Nadim Kanj, Ee Ming Khoo, Bruce Kirenga, Leonie Klompstra, Martha Kyriakou, Bouchra Lamia, Le Thi Tuyet Lan, Dominik Linz, Angela H.E.M. Maas, Angela Massouh, Walter Mattarucco, Renata Gonçalves Mendes, Anant Mohan, Trine Moholdt, Majid Mokhtari, Felicia Montero-Arias, C Münks-Lederer, Shigeo Muro, Kazuhiro Nakao, Yoko M. Nakao, Thu Nguyen Ngoc Phuong, Demosthenes B. Panagiotakos, Alberto Papi, Gerardo Payró, Massimo Piepoli, Marija Polovina, Bogdan A Popescu, David Price, Hany Ragy, Keerthenan Raveendra, Christopher M. Reid, Catherine Reynolds, Antônio Luiz Pinho Ribeiro, Richard Russell, Lavanya Saiva, Juliana Salas Segura, Julie Sanders, R.J. Scott, Terence Seemungal, Dinesh Shrikrishna, Sami O. Simons, Yuanlin Song, Abirami Subramaniam, Yongchang Sun, Raj Thakkar, Frederik Trinkmann, Izabella Uchmanowicz, Viola Vaccarino, Lowie E.G.W. Vanfleteren, Rajesh Vedanthan, Tonya Winders, Jianhua Wu, Jinping Zheng, Min Zhou

Bibliographic record

VenueEuropean Journal of Preventive Cardiology · 2025
Typearticle
Languageen
FieldMedicine
TopicChronic Obstructive Pulmonary Disease (COPD) Research
Canadian institutionsUniversity of ManitobaUniversity of AlbertaUniversity of SaskatchewanMcGill University Health CentreUniversity of British Columbia
Fundersnot available
KeywordsMedicineCOPDIntensive care medicineAtrial fibrillationExacerbationInternal medicinePhysical therapy

Abstract

fetched live from OpenAlex

AIMS: Cardiovascular disease is a common comorbidity in chronic obstructive pulmonary disease. Yet, cardiovascular disease and risk are underdiagnosed in chronic obstructive pulmonary disease and are often undertreated, increasing the risk of cardiopulmonary events. METHODS AND RESULTS: We formed a Global Working Group of experts in chronic obstructive pulmonary disease and cardiovascular disease to produce a consensus statement detailing the identification and management of cardiopulmonary risk in patients with chronic obstructive pulmonary disease. We conducted virtual meetings supplemented by remote working and communication. The Chairs (C.P.G., M.B.) proposed a draft consensus statement, which was further developed by the Global Working Group. The selection of the final consensus statement and key points were obtained using the modified Delphi method. The consensus statement is, 'Given the high burden of fatal and non-fatal major cardiovascular and respiratory events in patients with COPD it is important that cardiopulmonary risk is assessed and managed'. Patients with cardiovascular risk factors or disease who have regular cough or expectoration, recurrent 'chest infections', a significant smoking history, or dyspnoea should complete spirometry to confirm the presence of chronic obstructive pulmonary disease. Prevalent and incident cardiovascular disease and risk in patients with chronic obstructive pulmonary disease, including heart failure, dyslipidaemia, hypertension, ischaemic heart disease, and atrial fibrillation, should be managed according to clinical guidelines. In addition, chronic obstructive pulmonary disease exacerbation risk in patients with chronic obstructive pulmonary disease should be addressed to reduce cardiopulmonary risk. Enhanced integration with specialists in cardiology, pulmonology, and primary care is recommended. CONCLUSION: The identification and management of cardiopulmonary risk in patients with chronic obstructive pulmonary disease are an unmet public health need that can be addressed through shared understanding and multidisciplinary working to improve cardiopulmonary outcomes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.030
Threshold uncertainty score0.807

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.278
Teacher spread0.267 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations24
Published2025
Admission routes1
Has abstractyes

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