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Record W4408251692 · doi:10.1016/j.wneu.2025.123878

Safety and Feasibility of Transabdominal Muscle Action Potential Monitoring in Lateral Lumbar Surgery

2025· article· en· W4408251692 on OpenAlexaff
Kaveh Khajavi, Jim A. Youssef, Robert K. Eastlack, Jeffrey Balzer, Greg Niznik, William D. Smith

Bibliographic record

VenueWorld Neurosurgery · 2025
Typearticle
Languageen
FieldMedicine
TopicIntraoperative Neuromonitoring and Anesthetic Effects
Canadian institutionsCytodiagnostics (Canada)
FundersNuVasive
KeywordsMedicineLumbarSurgery

Abstract

fetched live from OpenAlex

BACKGROUND: Neuromonitoring has improved since its advent in the 20th century, but technological innovations can potentially become furthermore specific and perform advanced analyses to prevent nerve injury. PURPOSE: To assess the viability of a novel intraoperative neuromonitoring modality - transabdominal muscle action potential monitoring (TMAP) - to provide reliable monitoring of the cauda equina during lumbar spinal fusion. METHODS: This was a multicenter, prospective, single-cohort, technical feasibility study. A total of 296 patients who underwent one- or two-level lateral lumbar interbody fusion with TMAP neuromonitoring in the treatment of degenerative lumbar spinal disease were enrolled and analyzed. Lateral lumbar interbody fusion was performed at L4-L5 in all patients and at additional levels when needed. Triggered electromyography was utilized, per the surgical technique, to map the transpsoas surgical corridor. Additionally, TMAP was used to monitor bilateral lower extremity nerve function before, during, and at the end of surgery. The feasibility of TMAP to stimulate lower extremity myotomes was measured at baseline and through the procedure. RESULTS: In 296 patients included for final analysis, 98.9% of myotomes were activated at baseline and 98.6% of myotomes activated at closure. At least three myotomes were activated in all patients before and after surgery. All 10 myotomes were activated in 94% of patients at baseline and in 93% at closure. CONCLUSIONS: TMAP during lumbar spine surgery is feasible and safe for patients being treated for lumbar degenerative disease, while avoiding some of the drawbacks of transcranial motor evoked potentials. Additional studies are needed to assess clinical correlation between TMAP monitoring and patient outcome.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.228
Threshold uncertainty score0.601

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.033
GPT teacher head0.310
Teacher spread0.277 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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