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Record W4408254465 · doi:10.1016/j.tjnut.2025.03.004

Folic Acid-Containing Supplement Use among Females Aged 15–55 in the Canadian Community Health Survey 2015–2018

2025· article· en· W4408254465 on OpenAlexafffundabout
Kathryn E. Hopperton, Lidia Loukine, The Minh Luong, Loan Nguyen, Jesse Bertinato, Yvette Bonvalot, Marcia Cooper, Wei Luo, Amanda J MacFarlane, Jennifer McCrea, Carley Nicholson, Huma Rana, Kelsey A. Vercammen, Shawn Brule, Hope A. Weiler

Bibliographic record

VenueJournal of Nutrition · 2025
Typearticle
Languageen
FieldMedicine
TopicFolate and B Vitamins Research
Canadian institutionsStatistics CanadaPublic Health Agency of CanadaHealth Canada
FundersPublic Health Agency of Canada
KeywordsFolic acidMedicineEnvironmental healthGerontologyPhysiologyInternal medicine

Abstract

fetched live from OpenAlex

BACKGROUND: In Canada, those who are or who could become pregnant are recommended to consume a daily multivitamin containing 400 μg of folic acid to help prevent neural tube defects. OBJECTIVES: This study aims to report the prevalence and determinants of folic acid-containing supplement use among females of childbearing age in Canada. METHODS: Data were combined from cycles 2015/2016 and 2017/2018 of the maternal experiences module of the cross-sectional Canadian Community Health Survey, which was completed by females aged 15-55 y. Representative weighted estimates (means/percentages, 95% confidence interval) were generated for folic acid-containing supplement use among all pregnant, nonpregnant, and lactating respondents. For those who had given birth in the preceding 5 y, estimates were also generated for supplement use in the 3 mo before and first 3 mo of their most recent pregnancy, and prepregnancy awareness of the link between folic acid and some birth defects. We examined associations with sociodemographic factors using multivariable logistic regression. RESULTS: Overall, 16.5% (15.9%, 17.0%) of nonpregnant, 80.3% (77.1%, 83.5%) of pregnant, and 58.4% (54.8%, 61.9%) of lactating females aged 15-55 reported using a folic acid-containing supplement. Among those who had given birth in the preceding 5 y, 63.7% (62.2%, 65.1%) consumed a folic acid-containing supplement in the 3 mo before pregnancy, whereas 89.9% (88.8%, 90.9%) did so during the first trimester. A lower prevalence of supplement use before or during pregnancy was reported among the 23.7% (22.4%, 25.1%) of respondents unaware of the relationship between folic acid and birth defects. Younger age, single marital status, lower educational attainment, income below the median, and smoking were associated with lower odds of awareness or supplement use. CONCLUSIONS: Although most females living in Canada reported using folic acid-containing supplements prior to and during pregnancy, use of these supplements among nonpregnant females of childbearing age is low, and sociodemographic inequalities exist.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.010
Threshold uncertainty score0.075

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0020.004
Science and technology studies0.0010.000
Scholarly communication0.0010.000
Open science0.0010.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.132
GPT teacher head0.402
Teacher spread0.270 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes3
Has abstractyes

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