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Distribution of strength potential of the thumb muscles and their relationship to trapeziometacarpal osteoarthritis: An exploratory cadaveric study

2025· article· en· W4408274552 on OpenAlexaff
Mirka Normand, Mohammad Reza Effatparvar, Felix-Antoine Lavoie, Jean‐Michel Brismée, Stéphane Sobczak

Bibliographic record

VenueClinical Biomechanics · 2025
Typearticle
Languageen
FieldMedicine
TopicOrthopedic Surgery and Rehabilitation
Canadian institutionsUniversité du Québec à Trois-Rivières
Fundersnot available
KeywordsThumbCadaveric spasmMedicineOsteoarthritisAnatomyBody mass indexOrthodonticsPhysical medicine and rehabilitationInternal medicine

Abstract

fetched live from OpenAlex

BACKGROUND: The ten muscles of the thumb allow for a variety of movement combinations yielding similar functional outcomes yet using different load transmission with different biomechanical stresses resulting in heterogenous trapeziometacarpal wear patterns. Our exploratory study investigates the correlation between the severity and location of trapeziometacarpal joint osteoarthritis and estimated individual thumb muscles maximal force. METHOD: Normalized muscle mass to body mass and physiological cross-sectional area ratio were calculated following systematic muscular dissection of 19 cadaveric hands, 60 % males, average age 79.2, SD = 7.1. Correlations were analyzed with 3 different measures of articular degenerations. FINDINGS: Moderate negative correlation was found between Eaton-Glickel osteoarthritis grade and normalized muscle mass of opponens pollicis (rₛ = -0.59, p < .01) and abductor pollicis longus (rₛ = -0.60, p < .01). Moderate negative correlation was also found between trapeziometacarpal index and normalized opponens pollicis and abductor pollicis longus muscle mass (rₛ = -0.63, p < .01) and (rₛ = -0.51, p < .05), respectively. No correlation was identified between physiological cross-sectional area ratios and the above degeneration metrics. INTERPRETATION: Our current findings identified moderate negative correlations between the normalized mass to body mass of abductor pollicis longus and opponens pollicis for both Eaton-Glickel osteoarthritis grade and trapeziometacarpal index, which would support the current hand therapy exercise recommendations for the arthritic trapeziometacarpal population. Caution must be taken in the interpretation of correlations with articular zones degradation as our analytical power was reduced by the complete eburnation of few articular surfaces.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.745
Threshold uncertainty score0.275

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.036
GPT teacher head0.331
Teacher spread0.294 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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