Ubiquitous global use of persistent PFAS threatens Arctic Indigenous peoples for decades to come
Bibliographic record
Abstract
Per- and polyfluoroalkyl substances (PFAS) are found in the environment worldwide due to their ubiquitous usage, global transport, and biological persistence. Here, we estimate the temporal dietary exposure to long-range-transported PFAS during 2006–2020 in the East Greenland Ittoqqortoormiit (Scoresby Sound) community based on consumption of traditional marine foods as compared with internationally established tolerable weekly intake (TWI) for immune toxicity of 4.4 ng/kg body weight. We found a biomagnification factor of 4–10 between ringed seal:polar bear and estimate that ∼90% of the Ittoqqortoormiit community exceeded the established ∑ 4 PFAS TWI by 13-fold through consumption of polar bears and ringed seals. We estimate that the average inhabitant will continue to exceed established toxicity guidelines until 2090, posing the risk of immune suppression and disease susceptibility. Our findings emphasize the need for additional regulation of PFAS and the development of non-toxic sustainable compounds through international collaboration, not least through the Stockholm Convention.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".