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Record W4408300572 · doi:10.2166/h2oj.2025.037

Synergistic antimicrobial mechanisms of silver-doped zinc oxide for water treatment: a systematic review

2025· review· en· W4408300572 on OpenAlexaff
Elizabeth Makauki, Revocatus L. Machunda, Onita D. Basu, Mwemezi J. Rwiza

Bibliographic record

VenueH2Open Journal · 2025
Typereview
Languageen
FieldNursing
TopicChild Nutrition and Water Access
Canadian institutionsCarleton University
Fundersnot available
KeywordsAntimicrobialZincDopingChemistryMedicineNanotechnologyMaterials scienceMicrobiologyBiology

Abstract

fetched live from OpenAlex

This systematic review provides an overview of the existing research on antimicrobial mechanisms of silver-doped zinc oxide nanocomposites (Ag/ZnO NCs). It reports the existing knowledge on the synergistic effect (relationship) between silver (Ag) and zinc oxide (ZnO) for its optimum application. The doping of Ag into the ZnO has been used to enhance its photocatalysis and antimicrobial performance by improving the generation of reactive oxygen species (ROS). The Ag/ZnO NCs' microbial elimination can be done through generated ROS, metallic (Ag+ and Zn2+) ions, and direct attack by the nanoparticles (NPs). Unlike the summation of individual use outcomes, the antimicrobial results of Ag/ZnO create a synergetic effect. This brings the sustainable use of the materials by increasing their efficiency while lowering the amounts used. This article systematically reviews the antimicrobial mechanisms of Ag/ZnO against gram-negative and gram-positive bacteria. It further analyses the quantitative and qualitative synergism between Ag and ZnO when applied together as antimicrobial materials. This systematic review found Ag/ZnO as a potential microbial elimination agent. Many studies reported the chemical synthesis of Ag/ZnO, which might cause a yield of toxic nanomaterials. Further studies on biosynthesis are pivotal for the sustainable supply of safe, non-toxic materials aimed at drinking water treatment.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.006
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.005
Threshold uncertainty score0.014

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.006
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0030.004
Bibliometrics0.0050.004
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0040.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.039
GPT teacher head0.339
Teacher spread0.299 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations6
Published2025
Admission routes1
Has abstractyes

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