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Record W4408312721 · doi:10.1016/j.health.2025.100390

A comparative study of explainable machine learning models with Shapley values for diabetes prediction

2025· article· en· W4408312721 on OpenAlexaff
Keona Pang

Bibliographic record

VenueHealthcare Analytics · 2025
Typearticle
Languageen
FieldComputer Science
TopicMachine Learning in Healthcare
Canadian institutionsMcMaster University
Fundersnot available
KeywordsDiabetes mellitusComputer scienceMachine learningArtificial intelligenceEconometricsMedicineMathematicsEndocrinology

Abstract

fetched live from OpenAlex

Over the years, numerous machine learning models have been developed, leading to successful applications across various fields. This study uses a large dataset related to type 2 diabetes prediction from the Centers for Disease Control and Prevention (CDC) in the United States. The dataset with 70692 samples has 21 input features and one output (non-diabetes or diabetes). In addition to health indicators like Body Mass Index (BMI), blood pressure, and cholesterol level, the features include socioeconomic factors (e.g., income, education) and lifestyle factors such as diet and physical activity. This paper aims to study how these features influence diabetes risk. 80% of the dataset is used for training and 20% for testing. Six machine learning models, as well as the Multivariate Adaptive Regression Splines (MARS) model, were used in the investigation. A detailed comparison of the performance of these models is given. Shapley values explain the nature of various machine learning models using visualization by color graphs to demonstrate the reliability of different machine learning models. This paper shows how Shapley values can improve their explainability and interpretability on diabetes prediction. We leverage the SHapley Additive exPlanations (SHAP) scores to provide information about the relative importance of each predictive feature, and these results shed light on the relationship between the features and the risk of developing type 2 diabetes. • Use a large dataset with 70692 samples and 21 input features in machine learning for type 2 diabetes prediction. • Present detailed discussions on the Multivariate Adaptive Regression Splines (MARS) model. • Show good prediction performance for six machine learning models and the MARS model. • Use SHapley Additive exPlanations (SHAP) scores to provide information about the relative importance of each predictive feature. • Improve the explainability and interpretability of the machine learning model.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.595
Threshold uncertainty score0.825

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.070
GPT teacher head0.343
Teacher spread0.273 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations13
Published2025
Admission routes1
Has abstractyes

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