Biological Synthesis of Reusable Silver Nanoparticle‐Protein Antimicrobial Films
Bibliographic record
Abstract
Abstract Silver nanoparticles (AgNPs) are used in electronics, medical and environmental applications. However, the toxicity of AgNPs in humans and the environment is a cause of concern. To address this, AgNPs are incorporated into nanocomposites to control their release and activity. As such, it is proposed to use curli fibers as a biological scaffold to integrate AgNPs. Curli fibers are amyloid proteins present in bacterial biofilms. Due to their adherence to many surfaces, they can facilitate their interaction with a range of nanomaterials. Curli films are manufactured by crosslinking them with glutaraldehyde and subsequently synthesizing AgNPs. By changing the precursor concentrations, the content of AgNPs synthesized is modulated. Curli‐AgNP films are stable in pHs between 3–11 and in different solvents for 24 h. The release of AgNPs is greatest in alkaline pHs, with practically no release in acidic conditions. Additionally, curli‐AgNP films display antimicrobial activity against E scherichia coli (E. coli) and Bacillus subtilis ( B . subtilis) , and the same film can be re‐used multiple times against growing bacterial cultures. The ease of synthesis of curli‐AgNP films coupled with their impressive stability, variable AgNPs release, and strong antimicrobial properties are suitable qualities that can be exploited to aid in wound healing or water treatment applications.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".