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Record W4408403324 · doi:10.1136/bmjsem-2025-002529

Physiological outcomes of physical activity interventions in persistent postconcussive symptoms: a scoping review protocol

2025· review· en· W4408403324 on OpenAlexaff
Bayan Dehghani, Jyotpal Singh, Chase J. Ellingson, J. Patrick Neary

Bibliographic record

VenueBMJ Open Sport & Exercise Medicine · 2025
Typereview
Languageen
FieldMedicine
TopicTraumatic Brain Injury Research
Canadian institutionsUniversity of ReginaGenome Prairie
Fundersnot available
KeywordsPsycINFOPsychological interventionMEDLINEMedicineCochrane LibraryScopusCINAHLProtocol (science)Intervention (counseling)Systematic reviewRehabilitationPhysical therapyPsychologyAlternative medicineNursingPathology

Abstract

fetched live from OpenAlex

There are limited therapeutic options for patients with persistent postconcussive symptoms (PPCSs). Most PPCS assessments focus on subjective measures of progression and symptom monitoring. While early exercise interventions for rehabilitation are now considered best practice for acute concussion, no comprehensive review exists on how physical activity objectively and physiologically affects outcomes in PPCS. This scoping review protocol outlines the methods to identify the efficacy of therapeutic exercise interventions for PPCS, emphasising their impact on physiological parameters, including cardiovascular autonomic responses and cerebral autoregulation. Using the Patient, Intervention, Comparison and Outcome (PICO) framework, we will include all studies presenting original data. Narrative summaries will provide clinicians. An initial search in Medline/EMBASE/PubMed, Cochrane Library, PsycINFO, Web of Science and Scopus will be completed. Key parameters from each study will be extracted, tabulated and discussed in a narrative inquiry. The study references will be reviewed for additional studies meeting the inclusion criteria. Future research applications from the findings will be emphasised. After completion of the review, the results will be stratified by type of physical activity as the intervention, emphasising the physiological outcomes. Mapping these findings will allow us to identify the key research priorities for future studies. Findings will be shared with PPCS practitioners and local/national committees and submitted for conferences and publications.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Meta-epidemiology (broad), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.429
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.002
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0180.003
Bibliometrics0.0010.002
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.303
GPT teacher head0.577
Teacher spread0.275 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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