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Record W4408476467 · doi:10.1016/j.tjpad.2025.100134

Brain health PRO/Santé cerveau PRO: The development of a web-based program for dementia literacy and risk factor reduction

2025· article· en· W4408476467 on OpenAlexafffundabout
Sylvie Belleville, Nicole D. Anderson, Louis Bherer, Richard Camicioli, Julie Carrier, Senny Chan, Marc Cuesta, Thien Thanh Dang‐Vu, Emily Dwosh, Alexandra Fiocco, Guylaine Ferland, Bobby Gilbert, Elaine Harris, Inbal Itzhak, Pamela Jarrett, Danielle Laurin, Teresa Liu‐Ambrose, Chris A. McGibbon, Laura E. Middleton, Lesley Ellis Miller, Haakon B. Nygaard, Manuel Montero‐Odasso, Kelly J. Murphy, Natalie A. Phillips, M. Kathleen Pichora‐Fuller, Julie M. Robillard, Eric E. Smith, Mark Speechley, Amal Trigui, Walter Wittich, Howard Chertkow, Howard Feldman

Bibliographic record

VenueThe Journal of Prevention of Alzheimer s Disease · 2025
Typearticle
Languageen
FieldMedicine
TopicDementia and Cognitive Impairment Research
Canadian institutionsUniversity of CalgaryUniversité de MontréalUniversity of New BrunswickVancouver Coastal HealthParkwood InstituteUniversity of WaterlooCentre de Santé et de Services Sociaux de la Vieille-CapitaleClinique Paro ExcellenceLawson Health Research InstituteInstitute for Christian StudiesMontreal Heart InstituteUniversity of British ColumbiaUniversity of TorontoHorizon Health NetworkInstitut Universitaire de Gériatrie de MontréalConcordia UniversityHôpital du Sacré-Cœur de MontréalJewish General HospitalWomen and Children’s Health Research InstituteBaycrest Hospital
FundersCanadian Institutes of Health ResearchFonds de Recherche du Québec-Société et CultureAssessment Systems CorporationConsortium canadien en neurodégénérescence associée au vieillissement
KeywordsDementiaHealth literacyRisk factorLiteracyReduction (mathematics)PsychologyMedicineHealth careInternal medicinePolitical scienceDisease

Abstract

fetched live from OpenAlex

BACKGROUND: Online educational programs focused on ways to improve brain health could increase participant literacy, empowerment, and engagement in activities that support personal brain health, potentially reducing dementia risk. OBJECTIVES: Our goal was to develop an evidence-based online educational program with a focus on risk and protective factors for dementia. Here we present the rationale and features of the program and include results from a pilot study that assessed usability and acceptability. DESIGN: This project is part of the Can-Thumbs UP (CTU) initiative. An Intervention Mapping Approach framework and co-construction approach was used to develop the online program. A pre-post pilot open label design was used to test the usability and acceptance of this at-home educational program. SETTING: The program and assessment for the pilot study were delivered fully remotely. PARTICIPANTS: Twenty community-dwelling older adults (60-83 years of age, 65 % female) living in Canada who were at increased risk of dementia. PROGRAM: The Brain Health PRO/Santé Cerveau PRO is a web-based 45-week program available in French and English. It provides general information and guidance on seven modifiable risk factors for dementia: physical activity, nutrition, cognitively stimulating activities, sleep, social and psychological health, vascular health, and vision/hearing. After completing a brief intake questionnaire, users are provided with an individualized risk profile to personalize priorities and goals. During the course of the program, users receive feedback on lifestyle changes. For this pilot study, participants completed a 15-week version of the program. MEASUREMENTS: This pilot study reports measures of usability (System Usability Scale), acceptance (Technology Acceptance Model-2) as well as risk profiles at intake based on self-reported questionnaires. RESULTS: Two logic models were developed to identify the determinants of risk for dementia and how these could be targeted by the program. A review of dementia risk and protective factors and online educational programs for older adults, as well as co-creation activities with experts, stakeholders, and citizen advisors, were used to identify the determinants, target, format, and content of the program. The pilot study reports excellent usability and acceptance with scores of 80.4/100 and 93.5/120 respectively. CONCLUSION: Intervention mapping and co-construction approaches facilitated the design of a program that effectively balances the delivery of scientific content with the specific constraints, needs and abilities of older adults. TRIAL REGISTRATION: NCT05347966.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.945
Threshold uncertainty score0.275

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.033
GPT teacher head0.403
Teacher spread0.370 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2025
Admission routes3
Has abstractyes

Explore more

Same venueThe Journal of Prevention of Alzheimer s DiseaseSame topicDementia and Cognitive Impairment ResearchFrench-language works237,207