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Record W4408524483 · doi:10.1093/cid/ciae653

State-of-the-Art Review: Recurrent Uncomplicated Urinary Tract Infections in Women

2025· review· en· W4408524483 on OpenAlexaboutno aff
Sonali D. Advani, Joshua T. Thaden, Reinaldo Perez, Sabrina L. Stair, Una Lee, Nazema Y. Siddiqui

Bibliographic record

VenueClinical Infectious Diseases · 2025
Typereview
Languageen
FieldMedicine
TopicUrinary Tract Infections Management
Canadian institutionsnot available
FundersDuke Claude D. Pepper Older Americans Independence Center, Duke Aging Center, Duke UniversityCenters for Disease Control and PreventionbioMérieuxBoston Scientific JapanNational Institute of Allergy and Infectious DiseasesSociety for Healthcare Epidemiology of AmericaNational Institute on AgingBoston Scientific CorporationAmerican Urogynecologic SocietyGlaxoSmithKlineNational Institute of Diabetes and Digestive and Kidney DiseasesViiV HealthcareInfectious Diseases Society of America
KeywordsMedicineEpidemiologyEtiologyUrinary systemIntensive care medicineDiseasePopulationInfectious disease (medical specialty)Narrative reviewQuarter (Canadian coin)Internal medicineGynecologyFamily medicinePediatricsEnvironmental health

Abstract

fetched live from OpenAlex

Over 50% of adult women experience at least 1 urinary tract infection (UTI) in their lifetime, and almost one-quarter of them will experience a recurrent UTI (rUTI). Recurrent UTI is defined as ≥2 UTIs in a 6-month period or ≥3 UTIs in 12 months (at least 1 of these episodes should be culture-proven to confirm infectious etiology). In this narrative review, we discuss the epidemiology, pathogenesis, diagnosis, and treatment considerations for recurrent uncomplicated cystitis in the adult female population. We provide a focused overview of the comprehensive management of these patients, with input from infectious disease physicians, urogynecologists, and urologists with expertise in rUTI, highlighting updated recommendations by the Infectious Diseases Society of America, American Urologic Association, Canadian Urologic Association, and American Urogynecologic Society. Finally, given the variety of prevention strategies, different treatment goals, and the need for "preference sensitive" decisions, we highlight the need for shared decision-making with patients.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.006
Threshold uncertainty score0.020

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0030.004
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0060.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.061
GPT teacher head0.429
Teacher spread0.368 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations27
Published2025
Admission routes1
Has abstractyes

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