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Record W4408634710 · doi:10.1097/pec.0000000000003336

Predicting Future Acute Care Visit Risk in Kids With Asthma (PARKA)

2025· article· en· W4408634710 on OpenAlexaffabout
Dhenuka Radhakrishnan, Patricia Li, Meltem Tuna, Madhura Thipse, Vid Bijelić, Naveen Poonai, Dominic Chalut, Roger Zemek, Eric I. Benchimol, Francine M. Ducharme

Bibliographic record

VenuePediatric Emergency Care · 2025
Typearticle
Languageen
FieldMedicine
TopicAsthma and respiratory diseases
Canadian institutionsHospital for Sick ChildrenSickKids FoundationUniversity of TorontoUniversité de MontréalWestern UniversityMcGill University Health CentreOttawa HospitalMcGill UniversityChildren's Hospital of Eastern OntarioUniversity of Ottawa
Fundersnot available
KeywordsMedicineAsthmaEmergency departmentBrier scoreExacerbationAsthma exacerbationsProspective cohort studyCohortEmergency medicinePediatricsCohort studyInternal medicine

Abstract

fetched live from OpenAlex

OBJECTIVES: We aimed to develop a clinical risk score to predict future asthma acute care visits [emergency department (ED) visits or hospitalizations] within 1 year following a discharge from 1 of 2 tertiary care pediatric EDs in Ontario, Canada. METHODS: We assembled a nested Ontario cohort from the multicenter prospective DOORWAY cohort study and included children 1 to 17 years of age, with an ED visit for a moderate/severe asthma exacerbation. We linked this with provincial health administrative data. We used multivariable regression to derive and internally validate a practical clinical risk score to predict future asthma acute care visits. RESULTS: A total of 257 children [32% female, median age 3.0 years (IQR 1 to 7 y)] were included, and 58 experienced an asthma visit within the following year. These were best predicted by 4 factors: food allergy (OR 4.2, 95% CI: 1.2-14.9), family history of asthma (OR 0.5, 95% CI: 0.3-0.9), prior acute asthma medical visits (OR 2.8, 95% CI: 0.9-8.6), and prior emergency room visits for any respiratory diagnosis (OR 3.0, 95% CI: 1.4-6.4). A score of 0, 1, or 2 points was applied to each factor for up to a maximum of 6 points; the PARKA score has very good overall performance with a scaled Brier score of 0.11 on internal validation and good discrimination with an AUC of 0.72 (95% CI: 0.64-0.78). CONCLUSIONS: The PARKA score predicts the risk of a future asthma acute care visit in a cohort of Ontario children with a moderate/severe asthma ED visit. Following external validation, this tool may aid ED clinicians in accurately targeting resource-intensive preventative interventions for at-risk children.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.318
Threshold uncertainty score0.632

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0010.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.003
GPT teacher head0.253
Teacher spread0.250 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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