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Record W4408638286 · doi:10.1016/j.lana.2025.101056

Inequalities in paediatric hospitalisations for costly and prevalent conditions in Ontario, Canada: a population-based cohort study

2025· article· en· W4408638286 on OpenAlexafffundabout
Peter J. Gill, Thaksha Thavam, Jingqin Zhu, Cornelia M. Borkhoff, Patricia C. Parkin, Eyal Cohen, Teresa To, Sanjay Mahant

Bibliographic record

VenueThe Lancet Regional Health - Americas · 2025
Typearticle
Languageen
FieldHealth Professions
TopicFood Security and Health in Diverse Populations
Canadian institutionsInstitute for Clinical Evaluative SciencesHospital for Sick ChildrenPublic Health OntarioUniversity of Toronto
FundersMinistry of Long-Term CareCanadian Institutes of Health ResearchPhysicians' Services Incorporated FoundationInstitute for Clinical Evaluative SciencesHospital for Sick ChildrenCentre Hospitalier pour Enfants de l'est de l'OntarioKementerian Kesihatan MalaysiaImmigration, Refugees and Citizenship CanadaInstitut canadien d'information sur la santéMinistry of Health, Ontario
KeywordsCohortInequalityMedicineDemographyCohort studyPopulationPediatricsGeographyEnvironmental healthInternal medicineMathematicsSociology

Abstract

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Background: Identifying inequalities is important for informing research, and policy efforts to reduce health disparities. This study measured the inequalities in hospitalisations for the costly and prevalent conditions in hospitalised children using association estimates. Methods: Population-based cohort study using health administrative databases in Ontario, Canada between 2014 and 2019. The hospitalisation rate was determined for the costly and prevalent conditions in children. Hospitalisation inequalities by four equity stratifiers (material resources, rurality, sex, and immigrant status) were quantified using rate difference (RD), rate ratio (RR), and ratio of excess to total hospitalisation rate. Multivariable logistic regression analyses were also conducted. Findings: In a population of 3·7 million children (median age 7·0 years, Interquartile range: 1·0-12·0), there were 612,597 hospitalisations. Large inequalities comparing children among least versus most resourced quintile was observed in low birth weight (RD: 1,823·3 hospitalisations per 100,000 children, 95% CI: 1,662·7, 1,983·9). Conditions with large inequalities comparing rural versus urban areas included low birth weight (RD: -1,833·2 hospitalisations per 100,000, 95% CI: -2,012·8, -1,653·6); and drug withdrawal syndrome in newborn (RR: 1·9, 95% CI: 1·7, 2·1; adjusted odds ratio (aOR): 1·4, 95% CI: 1·2, 1·5). Conditions with large inequalities comparing males versus females included low birth weight (RD: -888·3 hospitalisations per 100,000, 95% CI: -992·5, -784·02); and anorexia nervosa (RR: 0·08, 95% CI: 0·07, 0·10; aOR: 0·1, 95% CI: 0.1, 0.1). Conditions with large inequalities comparing non-refugee immigrants versus non-immigrants included major depressive disorder (RR: 2·8, 95% CI: 2·7, 2·9), and comparing refugees versus non-immigrants included drug withdrawal syndrome in newborn (RR: 0·09, 95% CI: 0·05, 0·15). Results from multivariable analyses were similar. Interpretation: Newborn and mental health conditions had the largest inequalities in hospitalisations by the equity stratifiers. Findings from this study can be used to prioritise future health equity research to reduce health inequalities. Funding: PSI Foundation.

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How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.050
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.190
GPT teacher head0.457
Teacher spread0.267 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes3
Has abstractyes

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