Long-term impact of physical activity on the prevention of cognitive function decline: study protocol for an extended randomized controlled trial (PA Protect study)
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
The PA Protect study investigated the impact of increased daily physical activity on preventing cognitive decline, and maintaining healthy biomarker levels in individuals with mild cognitive impairment. Participants aged 50-70 years, selected based on their performance in the Montreal Cognitive Assessment test were enrolled in a double-blind randomized controlled trial and randomly assigned to either an active or passive group. The active group was instructed to achieve over 10,000 daily steps, while the passive group maintained usual activity levels. Preliminary findings revealed a positive influence of increased physical activity on cognitive function, with significant differences observed between the two groups in selected cognitive tests. Building on these results, this study extends the PA Protect trial for an additional three years. All participants will undergo cognitive assessments and biomarker analyses at the beginning and after the extended intervention period, providing further insights into long-term intervention effects.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.011 | 0.015 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it