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Record W4408697930 · doi:10.1289/ehp15788

Blood Lead Levels in Children 5 to 7 Years of Age from the Republic of Georgia: A Feasibility Study on Lead Surveillance Using Volumetric Absorptive Microsampling

2025· article· en· W4408697930 on OpenAlexaff
Charlotta Rylander, Erik Eik Anda, Ciprian Mihai Cirtiu, Tamar Jankhoteli, Nino Dzotsenidze, Vladimer Ghetia, Ekaterine Adamia, Paata Imnadze, Tinatin Manjavidze

Bibliographic record

VenueEnvironmental Health Perspectives · 2025
Typearticle
Languageen
FieldEnvironmental Science
TopicHeavy Metal Exposure and Toxicity
Canadian institutionsInstitut National de Santé Publique du Québec
Fundersnot available
KeywordsLead (geology)Environmental healthLead exposureMedicineEnvironmental scienceBiologyInternal medicine

Abstract

fetched live from OpenAlex

BACKGROUND: For years, children in the Republic of Georgia, have experienced elevated blood lead levels (BLLs). From September 2023 to April 2024, the National Center for Disease Control and Public Health in Georgia piloted a national surveillance program for lead in children in two western regions of the country, using volumetric absorptive microsampling (VAMS) to measure BLLs. OBJECTIVES: We monitored BLLs and assessed predictors of elevated BLLs in children 5-7 years of age from two regions in the Republic of Georgia. We also aimed to demonstrate the feasibility of VAMS for BLL surveillance. METHODS: in Georgia. RESULTS: . DISCUSSION: Our findings confirm that lead exposure remains a significant public health issue in two regions of the Republic of Georgia, despite a national decrease in BLLs over the past 5 years. To our knowledge, this research marks the first large-scale application of VAMS technology for national BLL surveillance, offering significant advantages as a less invasive lead testing method that is accurate and suitable for settings with limited resources to handle, store, and transport venous blood samples. https://doi.org/10.1289/EHP15788.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.134
Threshold uncertainty score0.266

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.037
GPT teacher head0.321
Teacher spread0.284 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes1
Has abstractyes

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