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Record W4408738723 · doi:10.1177/17531934251325654

UK Hand and Upper Limb Transplant Service, functional outcomes of the first six patients: A case series

2025· article· en· W4408738723 on OpenAlexaboutno aff
Joanna Burdon, Sarah Taplin, David A. Leonard, Ibrahim Natalwala, Gráinne Bourke, Simon Kay

Bibliographic record

VenueJournal of Hand Surgery (European Volume) · 2025
Typearticle
Languageen
FieldMedicine
TopicOrgan and Tissue Transplantation Research
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineUpper limbPhysical therapySurgeryGrip strengthPhysical medicine and rehabilitation

Abstract

fetched live from OpenAlex

To date, three unilateral and seven bilateral hand and upper limb transplants have been performed by the UK Hand Transplant Programme. We report functional outcomes for our first six patients, who have been followed for between 4 and 10 years. All patients gained protective sensation to pain, pressure and temperature, and a recordable power grip. All patients saw an improvement in the Canadian Occupational Performance Measure performance and satisfaction scores, with five out of six patients improving the Disability of the Arm Shoulder and Hand scores. The Hand Transplant Score System graded all distal transplants as either a ‘good’ or ‘excellent’ with proximal transplants scoring ‘fair’ or ‘good’. Hand transplant is an effective treatment in selected patients with continual improvements in function seen for up to 5 years. Level of evidence: IV

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.012
Threshold uncertainty score0.318

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.239
Teacher spread0.224 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes1
Has abstractyes

Explore more

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