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Record W4408841787 · doi:10.1242/jeb.249395

Using the reactive scope model to redefine the concept of social stress in fishes

2025· review· en· W4408841787 on OpenAlexafffund
Kathleen M. Gilmour, Carol Best, Suzanne Currie

Bibliographic record

VenueJournal of Experimental Biology · 2025
Typereview
Languageen
FieldImmunology and Microbiology
TopicAquaculture disease management and microbiota
Canadian institutionsUniversity of British Columbia, Okanagan CampusUniversity of British ColumbiaUniversity of GuelphUniversity of Ottawa
FundersNatural Sciences and Engineering Research Council of Canada
KeywordsAgonistic behaviourAggressionScope (computer science)PsychologySocial stressFight-or-flight responseDevelopmental psychologyEcologyBiology

Abstract

fetched live from OpenAlex

The term 'social stress' has traditionally referred to physiological stress responses induced by the behaviour of conspecifics, particularly aggression or agonistic behaviours. Here, we review the physiological consequences of social status in fishes using the reactive scope model (RSM) to explain the divergent physiological phenotypes of dominant and subordinate fish. The RSM plots levels of different physiological mediators (e.g. behaviour, glucocorticoid hormones) over time, using them to define functional ranges that differ in their consequences for the animal. We discuss differences in growth, reproduction and tolerance of environmental challenges, all of which are suppressed in subordinate individuals, and focus on the underlying mechanisms that give rise to these phenotypes. Repeated and/or continual activation of the hypothalamic-pituitary-interrenal (HPI) axis in subordinate fish can lead to prolonged elevation of cortisol, a key physiological mediator. In turn, this increases physiological 'wear and tear' in these individuals, lowering their reactive scope (i.e. the physiological range of a healthy animal) and increasing their susceptibility to homeostatic overload. That is, they experience social stress and, ultimately, their capacity to cope with environmental challenges is limited. By contrast, reactive scope is maintained in dominant individuals, and hence they are better able to tolerate environmental challenges. Redefining social stress in terms of the RSM allows us to overcome the ambiguities and limitations associated with the concept of stress.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Review · Consensus signal: none
Teacher disagreement score0.003
Threshold uncertainty score0.008

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.000
Science and technology studies0.0000.004
Scholarly communication0.0010.002
Open science0.0010.002
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.060
GPT teacher head0.378
Teacher spread0.318 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations6
Published2025
Admission routes2
Has abstractyes

Explore more

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