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Record W4408891609 · doi:10.1186/s13256-025-05188-0

Seven-month persistence of COVID-19 vaccine-induced lymphadenopathy: a case report

2025· article· en· W4408891609 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueJournal of Medical Case Reports · 2025
Typearticle
Languageen
FieldMedicine
TopicLymphadenopathy Diagnosis and Analysis
Canadian institutionsUniversity of TorontoUniversity Health NetworkHealth Sciences CentreSinai Health SystemSunnybrook Health Science CentreHospital for Sick Children
Fundersnot available
KeywordsMedicineCoronavirus disease 2019 (COVID-19)Persistence (discontinuity)Surgical oncology2019-20 coronavirus outbreakVirologySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)ImmunologyInternal medicineInfectious disease (medical specialty)Disease

Abstract

fetched live from OpenAlex

BACKGROUND: Lymphadenopathy is a known side effect of both messenger RNA and viral vector coronavirus disease-2019 vaccines and can cause a spectrum of findings. Coronavirus disease-2019 vaccine-associated lymphadenopathy typically resolves within 60 days after administration of the dose. CASE PRESENTATION: A 59 year old Chinese woman underwent routine mammographic screening that revealed scattered areas of fibroglandular densities in the lower-inner quadrant of the left breast and abnormal lymph nodes. A core biopsy of the breast identified ductal carcinoma in situ. A biopsy of the lymph nodes was performed, and histological findings and immunophenotype were consistent with lymphoid hyperplasia. This patient had sought medical attention after she detected swelling in her left supraclavicular fossa 7 months earlier. She had received the first dose of the Pfizer coronavirus disease-2019 vaccine in the left deltoid muscle 7 days prior to presenting with left supraclavicular fossa swelling. CONCLUSION: After reviewing the history, imaging, and pathology, it was concluded through a diagnosis of exclusion that the observed enlarged left axillary lymph nodes with reactive histology were probably related to the coronavirus disease-2019 vaccine administration and not to ductal carcinoma in situ or an undetected invasive cancer. Clinicians and radiologists need to be aware of the potential for abnormal presentations of persistent lymphadenopathy that may interfere with the diagnosis and follow-up of cancers.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.018
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.020
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0050.018
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.031
GPT teacher head0.346
Teacher spread0.315 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it