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Record W4408960622 · doi:10.1002/jvc2.70026

Role of Topical Ketoconazole in Therapeutic Hair Care Beyond Seborrhoeic Dermatitis and Dandruff

2025· article· en· W4408960622 on OpenAlexaff
Aditya K. Gupta, Piet De Doncker, Mesbah Talukder

Bibliographic record

VenueJEADV Clinical Practice · 2025
Typearticle
Languageen
FieldMedicine
TopicNail Diseases and Treatments
Canadian institutionsMediprobe Research (Canada)University of Toronto
Fundersnot available
KeywordsDandruffSeborrhoeic dermatitisKetoconazoleDermatologySeborrheic dermatitisMedicineShampooAntifungalPathology

Abstract

fetched live from OpenAlex

ABSTRACT Ketoconazole shampoo has well‐documented consistent efficacy and safety in treating dandruff and seborrhoeic dermatitis (SD) when compared to other active antidandruff ingredients such as selenium sulphide, corticosteroids and zinc pyrithione. Clinical superiority of ketoconazole shampoo has been demonstrated in several double‐blind, randomized studies. This article delves into the broader applications of ketoconazole shampoo in hair care beyond its established role in managing SD and dandruff. Ketoconazole may help reduce hair shedding, particularly in conditions like SD and dandruff. Ketoconazole shampoo can also help reduce chronic scalp inflammation that may otherwise cause hair follicle damage and hair loss. Its anti‐androgen properties offer significant potential in reducing hair shedding and promoting healthier hair growth. Ketoconazole shampoo may serve as a complementary treatment to minoxidil and finasteride in the management of androgenetic alopecia. These properties make ketoconazole shampoo a logical option for comprehensive scalp and hair care.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.106
Threshold uncertainty score0.356

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.409
Teacher spread0.392 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations6
Published2025
Admission routes1
Has abstractyes

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