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Record W4408997002 · doi:10.1302/1358-992x.2025.2.034

SHOULD WE BE ROUTINELY SCREENING FOR SYSTEMIC OSTEOPENIA FOLLOWING TOTAL HIP ARTHROPLASTY?

2025· article· en· W4408997002 on OpenAlexaboutno aff
Gary Mundy, Bill Robertson-Smith

Bibliographic record

VenueOrthopaedic Proceedings · 2025
Typearticle
Languageen
FieldMedicine
TopicOrthopedic Infections and Treatments
Canadian institutionsnot available
Fundersnot available
KeywordsOsteopeniaMedicineTotal hip arthroplastyHip arthroplastyArthroplastyPhysical therapyInternal medicineSurgeryOsteoporosisBone mineral

Abstract

fetched live from OpenAlex

Periprosthetic fractures (PPF) following total hip arthroplasty (THA) are increasing in prevalence with significant morbidity and mortality for the patient. PPF risks include increasing age, female sex, inflammatory arthropathy and osteopenia. Falls from standing height resulting in PPF following THA are by definition fragility fractures and such patients fulfil the criteria for a diagnosis of osteoporosis. The prevalence of screening, diagnosis, and treatment of systemic osteoporosis/osteopenia in patients before presentation with a periprosthetic fracture following THA is however unclear. We utilised our prospective database of PPF to identify patients presenting with a PPF following THA to a district general hospital over a 14-year period between January 2011 and January 2025. Data parameters collected included patient demographics, co-morbidities, fracture classification, use of HRT, steroid, calcium supplements, or bisphosphonates prior to the PPF, fracture management, timing of surgery and length of stay. We identified 296 PPFs following THA. 59% were in women with a mean age of 80 years and 41% in men with a mean age of 77 years. 19%, 48% and 32% were Mcpherson Systemic Host grade A,B and C respectively. At the time of presentation, no patients had documented FRAX scores, none were receiving HRT, 4% were receiving systemic steroids and only 17% bisphosphonates. Patients with Vancouver B2 (32%) and B3 (15%) fractures were taking bisphosphonates in only 17% and 9% of cases respectively. Type C (16%) and D (6%) received bisphosphonates in 26% and 23% respectively. Average length of stay was 27 days with the wait to surgery longest for B3 fractures at 7.5 days compared to 4.1 days for the B1 fractures. Periprosthetic fractures are an increasing burden to the NHS. We have identified deficiencies in screening and treating osteopenia in patients who have undergone THA. Additional resources directed at screening and treating osteopenia following THA may not only result in a lower incidence of this devastating complication but may also potentially reduce the incidence of other fragility fractures. We recommend surgeons undertaking THA have a role in raising awareness of screening for osteopenia.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.685
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.032
GPT teacher head0.303
Teacher spread0.271 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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