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Record W4409059729 · doi:10.1093/pch/pxae104

Illicit drug toxicity from opioid, stimulant or sedative use in adolescents: results of a Canadian one-time cross-sectional study

2025· article· en· W4409059729 on OpenAlexaffabout
Matthew Carwana, Eva Moore, Helia Shariati, Hasina Samji, Nicholas Chadi

Bibliographic record

VenuePaediatrics & Child Health · 2025
Typearticle
Languageen
FieldMedicine
TopicPoisoning and overdose treatments
Canadian institutionsUniversité de MontréalCentre Hospitalier Universitaire Sainte-JustineBC Children's HospitalSimon Fraser UniversityLearning PartnershipUniversity of British Columbia
FundersPublic Health Agency
KeywordsStimulantSedativeOpioidMedicineDrugPharmacologyInternal medicine

Abstract

fetched live from OpenAlex

Background: Illicit drug toxicity is an escalating public health emergency. Usually framed as an adult issue, adolescents are significantly impacted. Little is currently known about the interface between Canadian paediatric physicians and adolescents experiencing severe health events from illicit drug toxicity. Objectives: (1) To determine the proportion of paediatricians in Canada who care for young people between 12 and 18 years who have managed cases of illicit drug toxicity; (2) to identify the characteristics of paediatricians that provide this care; and (3) to describe respondents' awareness of substance use-oriented services for youth in their home communities. Methods: A one-time descriptive cross-sectional study was conducted from May to June 2022. Clinicians self-reported cases of illicit drug toxicity from opioids, stimulants and sedatives for adolescents 12 to 18 years old over the preceding 24-month period. Respondents also self-reported their knowledge of substance use-focussed services for children and adolescents in their communities. Results: = 934, 91%) reported providing medical care to children and youth 12 years of age and over. 128/934 (13.7%) reported caring for at least one case of illicit drug toxicity. The majority of case reporters were general paediatricians (43%). Overall awareness of substance-related services was limited. Conclusion: A considerable proportion of respondents provided care for illicit drug toxicity over 24 months. This contrasts with a relatively low level of awareness of services for substance use in this population. Further research and education can support patients and physicians alike in the care of adolescent illicit drug toxicity.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.056
Threshold uncertainty score0.113

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.002
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0020.005
Science and technology studies0.0030.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.031
GPT teacher head0.323
Teacher spread0.292 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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