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Record W4409073211 · doi:10.1093/jbcr/iraf019.084

84 A Proof-of-concept for a Continuous-temperature Circulating Water Bath in Frostbite Limb Rewarming

2025· article· en· W4409073211 on OpenAlexaff
Robert Tracy McKenzie, Joshua Wong, Alexis Armour

Bibliographic record

VenueJournal of Burn Care & Research · 2025
Typearticle
Languageen
FieldMedicine
TopicThermoregulation and physiological responses
Canadian institutionsUniversity of Alberta
Fundersnot available
KeywordsFrostbiteMedicineSkin temperatureProof of conceptIntensive care medicineSurgeryAnesthesiaDermatology

Abstract

fetched live from OpenAlex

Abstract Introduction Frostbite treatment is challenging due to tissue damage from ischemia and crystal formation. The American Burn Association advises rapid rewarming in 38-42°C water, yet hospital implementation is inconsistent. Our objective is to facilitate this step of frostbite treatment with a proof-of-concept, descriptive study of a proposed continuous-temperature circulating (CTC) water bath. We hypothesize that this design will effectively rewarm chilled extremities within the requisite 30 minutes without requiring frequent monitoring and adjustment of water temperature. Methods We constructed a CTC water bath system with a reservoir and a continuous warming and circulating device (CWCD). Water and tissue temperature were monitored using a needle probe thermometer. Pigs’ feet were chilled and immersed in 39.0 °C water with or without a CWCD. Results Without a CWCD, tissue warmed from 3.2 ± 0.3 °C to 34.2 ± 0.2 °C over 30 minutes, with a final water temperature of 36.5 ± 0.1 °C. With a CWCD, tissue warmed from 2.7 ± 0.2 °C to 36.7 ± 0.2 °C, with a final water temperature of 39.1 ± 0.1 °C. Conclusions This study demonstrates that the CTC water baths maintained at 39.0 °C offer a reliable and effective method for rewarming hypothermic tissue within 30 minutes. Continuous water temperature at 39.0 °C proved crucial in achieving euthermic tissue warming. These findings suggest that our approach could provide a practical solution to the inconsistent and impractical nature of current frostbite rewarming methods in clinical settings. The highest factor contributing to rewarming compliance is temperature regulation. These are mitigated by the CTC water bath. Further studies are ongoing to validate these findings in clinical practice and explore scalability and feasibility. Applicability of Research to Practice This research demonstrates the effective rewarming of chilled tissues using a CTC water bath. Future research will focus on developing a portable CTC water bath for implementation in acute care settings in the initial treatment of frostbite. This device may be utilized further in paramedic vehicles/stations and rural clinics where patients need long transport to the regional burn centers. Funding for the Study N/A

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.009

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.051
GPT teacher head0.410
Teacher spread0.358 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2025
Admission routes1
Has abstractyes

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