MétaCan
Menu
Back to cohort
Record W4409074091 · doi:10.3171/case24777

Can posterior fossa decompression alone effectively treat Chiari malformation type I patients with even severe syringes? Illustrative cases

2025· article· en· W4409074091 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueJournal of Neurosurgery Case Lessons · 2025
Typearticle
Languageen
FieldMedicine
TopicSpinal Dysraphism and Malformations
Canadian institutionsMontreal Children's HospitalMcGill University Health Centre
Fundersnot available
KeywordsSyrinx (medicine)MedicineSyringomyeliaSurgeryDecompressionPosterior fossaSpinal cordMagnetic resonance imagingRadiology

Abstract

fetched live from OpenAlex

BACKGROUND: The benefit of posterior fossa decompression (PFD) alone (without duraplasty) for Chiari malformation type I (CM-I) remains controversial. Many neurosurgeons still open the dura when a syrinx is present, particularly for what appears to be a severe syrinx. Based on the existing literature, the authors hypothesized that even a severe syrinx would respond well to a PFD alone. OBSERVATIONS: In a proof-of-principle study, the authors prospectively included 4 patients with CM-I, aged 3-15 years, with severe symptomatic syringes (spanning multiple cervical/thoracic levels and/or focally expanding the spinal cord) to undergo PFD with pre- and postdissection intraoperative MRI (iMRI). In all cases, same-day postdissection iMRI cine images showed enhanced CSF flow compared with predissection iMRI findings. Three of the 4 patients showed early syrinx and symptom improvement (≤ 6 weeks); all showed improvements at long-term follow-up (≥ 2 years). The mean hospital length of stay (LOS) was 1.25 days, with no complications or repeat surgery needed, and the mean follow-up was 37.5 months. LESSONS: CM-I can be treated via PFD alone without duraplasty, even with a severe syrinx. Improved CSF flow is achieved intraoperatively, and the syrinx can significantly decrease over a 6-week to 1-year period postoperatively. Additional benefits include a low risk of complications and a short LOS. https://thejns.org/doi/10.3171/CASE24777.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.248
Threshold uncertainty score0.634

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.019
GPT teacher head0.288
Teacher spread0.270 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it