A Huge Primary Retroperitoneal Diffuse Large B-cell Lymphoma: A Case Report
Bibliographic record
Abstract
Retroperitoneal diffuse large B-cell lymphoma (DLBCL) is generally rare and often presents with late symptoms. A 60-year-old female presented with abdominal pain for 3 days with associated symptoms of altered bowel habits and constitutional symptoms. Physical examination was unremarkable. The blood investigations were generally within normal limits except for a 10-fold rise in serum CA-125. Transabdominal ultrasonography revealed an ill-defined lesion, with a cystic component within, at the inferior pole of the spleen. Computed tomography scan showed a large lobulated soft tissue tumour in the left retroperitoneal space with local infiltration to adjacent organs with multiple subcentimeter para-aortic and aortocaval lymph nodes. Laparotomy revealed a locally advanced retroperitoneal tumour measuring 10 x 10cm in size. The left retroperitoneal tumour was resected en-bloc with the left kidney, the spleen, the distal part of the pancreas and a part of the left diaphragm. Histopathological examination of the retroperitoneal tumour revealed a DLBCL (germinal centre type) as CD10, CD20, and BCL-6 were positive among all the markers, confirming the final diagnosis. She was started on CHOP regimen chemotherapy and is currently well. A complete en-bloc resection of the retroperitoneal lymphoma is recommended in fit patients with resectable retroperitoneal tumours. The decision between core needle biopsy and surgical resection should be made on a case-by-case basis following a multidisciplinary team approach discussion to achieve the best outcome for these patients.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".