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Global Trends in Research of Intestinal Cells and Type 2 Diabetes Mellitus: A Bibliometric and Visualized Analysis from 2004 to 2023

2025· article· en· W4409211055 on OpenAlexaboutno aff
Zhao‐Yang Li, Shuang Zhang, Rufan Cao, Bo Wu, Kangning Han, Wenhui Yang, Shiyao Chen, Xinyu Zhang, Xiaochun Han, Liangqing Guo

Bibliographic record

VenueEndocrine Metabolic & Immune Disorders - Drug Targets · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGut microbiota and health
Canadian institutionsnot available
Fundersnot available
KeywordsBibliometricsChinaWeb of scienceLibrary scienceMedicineMEDLINESocial sciencePolitical scienceSociologyComputer scienceLaw

Abstract

fetched live from OpenAlex

BACKGROUND: As a systemic metabolic disease, type 2 diabetes has gradually become a disease that seriously threatens human health and quality of life worldwide. Many studies have shown that its pathogenesis and treatment are closely related to intestinal cells. However, the research in this field lacks relevant bibliometric analysis. This study aims to review the knowledge structure and research hot spots on intestinal cells and type 2 diabetes and provide a new direction for its future research through bibliometric methods and visual knowledge maps. METHODS: Using the Web of Science Core Collection (WoSCC) database, we searched the related literature on intestinal cells and type 2 diabetes from 2004 to 2023, and made bibliometric analysis through VOSviewer, CiteSpace, the "Bibliometrix" R package, and Scimago Graphica. Combined with Bradford's Law, Price's Law, Lotka's Law, and Zipf's law, bibliometrics analysis was conducted on publication time, author, country/region, keywords, journals, and references related to publications in this field. RESULTS: A total of 394 articles were included from 51 countries, led by the United States and China. In the past 20 years, the publication of relevant literature has shown a steady growth trend. These articles are from 2486 authors. Among them, Ti-dong Shan and Tao Yu from China have published the most literature, the University of Toronto is the main research institution, the Journal of Biological Chemistry is the journal with the most common citations, and the most prominently cited article is Sugar absorption in the industry: the role of GLUT2. CONCLUSION: This study is the first bibliometric analysis that comprehensively summarizes the research trends and hot spots of intestinal cells and type 2 diabetes. This information determines the research hot spots and research frontiers in this field. The hot spots of research are "intestinal epithelial cells", "GLP-1", "SGLT-1", "GLUT2", and "intestinal endocrine cell", while "intestinal epithelial stem cells", "short-chain fatty acid", "bile acid" and "bariatric surgery" may be the focus of future research, which helps clinicians better understand the relationship between intestinal cells and type 2 diabetes, and provides a reference direction for future scholars in this field.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesBibliometrics
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.573
Threshold uncertainty score0.985

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0100.036
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.367
Teacher spread0.351 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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