Association between postpartum systemic inflammation and serum calcium in healthy multiparous dairy cows—An exploratory observational analysis
Bibliographic record
Abstract
× parity, and farm as a random effect. A stepwise backward elimination approach was applied to improve model parsimony. The lowest albumin and greatest haptoglobin and SAA concentrations were observed at d 2. The association of albumin with tCa varied quadratically over time. At d 0, 0.5, 1, and 2, as tCa decreased, albumin increased, but at d 4, 6, and 8 as tCa decreased, albumin also decreased. At d 0, 0.5, and 1, when tCa <1.7 mmol/L, tCa and haptoglobin were positively associated. Total calcium <1.7 mmol/L was not observed ≥d 2. After d 1, cows with lower tCa tended to have greater haptoglobin concentrations. The greatest concentration of SAA occurred when tCa was 1.9 mmol/L. Values of tCa <1.9 mmol/L were mainly observed at d 0. At d 0, and when tCa was <1.9 mmol/L, lower tCa was associated with lesser SAA concentration. However, when tCa was >1.9 mmol/L (93% and 99% of the values observed at d 2 and 4, respectively), lower tCa was associated with greater SAA concentration. The associations between tCa and markers of SI changed in the first 8 d of lactation in clinically healthy cows. Potential interventions to modulate hypocalcemia or SI, or both, should consider their interactions. Future studies should further explore the association of the degree and duration of hypocalcemia and SI to better understand the direction and mechanisms of this relationship.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".