Impact of drainage cannula type on patients’ fluid balance in venovenous extracorporeal membrane oxygenation: A historical cohort study
Why this work is in the frame
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Bibliographic record
Abstract
Objective : Positive fluid balance in patients on veno-venous extracorporeal membrane oxygenation (VV ECMO) is associated with increased mortality. Drainage insufficiency on VV ECMO is a common occurrence and managed with fluid administration. The use of multi-stage drainage cannulas may result in decreased drainage insufficiency, but it is unclear the effects this may have on patient fluid balance. Design : A historical cohort study was conducted on adult patients undergoing VV ECMO for acute respiratory failure in femoral-jugular configuration. Setting : Intensive Care Unit. Patients : Adult patients undergoing VV ECMO for acute respiratory failure. Interventions : Cumulative fluid balance in the first 7 days following initiation of VV ECMO was examined. The relationship between cumulative daily fluid balance over the first 7 days and type of drainage cannula was assessed using mixed methods linear regression. Measurements and Main Results : We included 82 consecutive patients between April 1st, 2020 and September 1st, 2022. 47 (57%) patients were treated with a single-stage drainage cannula. Our final model showed the use of a multi-stage cannula decreased fluid balance by 740 mL/day (95% CI: −1360 to −118, p = .02) compared to patients with a single-stage drainage cannula for the first 7 days. Conclusions : The use of multi-stage drainage cannulas resulted in improved fluid balance in patients on VV ECMO in the first 7 days.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it