MétaCan
Menu
Back to cohort
Record W4409425140 · doi:10.1371/journal.pcbi.1012946

A teaching proposal for a short course on biomedical data science

2025· article· en· W4409425140 on OpenAlexaff
Davide Chicco, Vasco Coelho

Bibliographic record

VenuePLoS Computational Biology · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetics, Bioinformatics, and Biomedical Research
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsComputer scienceData sciencePython (programming language)Exploratory data analysisContext (archaeology)Big dataHealth scienceOpen scienceProcess (computing)Artificial intelligenceData miningProgramming languageMedical educationMathematics

Abstract

fetched live from OpenAlex

As the availability of big biomedical data advances, there is a growing need of university students trained professionally on analyzing these data and correctly interpreting their results. We propose here a study plan for a master's degree course on biomedical data science, by describing our experience during the last academic year. In our university course, we explained how to find an open biomedical dataset, how to correctly clean it and how to prepare it for a computational statistics or machine learning phase. By doing so, we introduce common health data science terms and explained how to avoid common mistakes in the process. Moreover, we clarified how to perform an exploratory data analysis (EDA) and how to reasonably interpret its results. We also described how to properly execute a supervised or unsupervised machine learning analysis, and now to understand and interpret its outcomes. Eventually, we explained how to validate the findings obtained. We illustrated all these steps in the context of open science principles, by suggesting to the students to use only open source programming languages (R or Python in particular), open biomedical data (if available), and open access scientific articles (if possible). We believe our teaching proposal can be useful and of interest for anyone wanting to start to prepare a course on biomedical data science.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.523
Threshold uncertainty score0.418

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.041
GPT teacher head0.381
Teacher spread0.339 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

Explore more

Same venuePLoS Computational BiologySame topicGenetics, Bioinformatics, and Biomedical ResearchFrench-language works237,207