MétaCan
Menu
Back to cohort
Record W4409460171 · doi:10.26650/iuitfd.1567904

EFFECTS OF PLATELET-RICH PLASMA AND OZONE THERAPY ON PAIN AND QUALITY OF LIFE IN KNEE OSTEOARTHRITIS: A RETROSPECTIVE TRIAL

2025· article· en· W4409460171 on OpenAlexaboutno aff
Aylin Ayyıldız, Selda Çiftci İnceoğlu, Banu Kuran

Bibliographic record

VenueJournal of Istanbul Faculty of Medicine / İstanbul Tıp Fakültesi Dergisi · 2025
Typearticle
Languageen
FieldMedicine
TopicMedical and Biological Ozone Research
Canadian institutionsnot available
Fundersnot available
KeywordsOsteoarthritisPlatelet-rich plasmaMedicineOzone therapyOzonePhysical therapyQuality of life (healthcare)Internal medicinePlateletAlternative medicineMeteorologyGeographyPathology

Abstract

fetched live from OpenAlex

<strong>Objective:</strong> There are many methods for treating knee osteoarthritis (KOA). However, especially among conservative treatments, intra articular injection methods have not been shown to be superior to each other. In our study, we compared the effects of ozone therapy and platelet-rich plasma on pain and functionality. <strong>Material and Methods: </strong>This retrospective clinical study included patients aged 30-70 years who received ozone and Platelet-Rich Plasma (PRP) for the treatment of knee osteoarthritis. Both groups received 3 sessions of ultrasound-guided intra-articular injection. The demographic characteristics of the patients, such as age and gender, were recorded. Pain was assessed with a numerical rating scale (NRS) before and 3 months after treatment, functionality with the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and quality of life with the Short Form-12 (SF-12). <strong>Results:</strong> The mean age of the 54 patients included in the study was 58.53±8.25 years. No significant difference was found between the two groups in terms of age, gender, pre-treatment NRS, WOMAC, and SF-12 values. There were significant differences in the NRS, WOMAC, and SF-12 values in both ozone and PRP groups after treatment compared to before treatment. However, this difference was not found to be significant between the groups. <strong>Conclusion:</strong> Both PRP and ozone therapy are effective short term treatments for KOA. There is no evidence that one is more effective than the other.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.021
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.413
Threshold uncertainty score0.987

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0060.021
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0030.000
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.039
GPT teacher head0.350
Teacher spread0.312 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designRandomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

Explore more

Same venueJournal of Istanbul Faculty of Medicine / İstanbul Tıp Fakültesi DergisiSame topicMedical and Biological Ozone ResearchFrench-language works237,207