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Record W4409478921 · doi:10.1080/21622965.2025.2490101

Predictors of neurocognitive outcome following childhood hemorrhagic stroke in the left hemisphere: A case series

2025· article· en· W4409478921 on OpenAlexaff
Leila Kahnami, Claire M. Champigny, Hiba Al-Hakeem, Mary Desrocher, Kaitlyn M. Butterfield, Naddley Désiré, Nomazulu Dlamini, Samyami S. Chowdhury, Peter B. Dirks, Robyn Westmacott

Bibliographic record

VenueApplied Neuropsychology Child · 2025
Typearticle
Languageen
FieldMedicine
TopicBlood Coagulation and Thrombosis Mechanisms
Canadian institutionsUniversity of WindsorHospital for Sick ChildrenYork University
Fundersnot available
KeywordsNeurocognitiveStroke (engine)PsychologyPhysical medicine and rehabilitationPsychiatryCognitionMedicine

Abstract

fetched live from OpenAlex

Neurocognitive deficits commonly occur following hemorrhagic stroke in childhood, yet the understanding of recovery patterns and prognostic factors remains limited. Hematoma location, lateralization, volume, and age at injury have been identified as predictors of neurocognitive outcomes. This case review aims to describe and discuss the influence of these factors on neurocognitive outcomes following hemorrhagic stroke in three pediatric cases. Three patients (one female age 13, two males ages 15 and 17) with a history of childhood hemorrhage were selected from a larger cohort due to their similar etiology (i.e., arteriovenous malformation) and similar lesion location (i.e., broadly within the temporoparietal region). Participants completed a neuropsychological assessment evaluating verbal comprehension, perceptual reasoning, processing speed, working memory, verbal fluency, language, learning, memory, and executive functioning. Results suggest variable language outcomes despite similar clinical characteristics. Both Case 1 and Case 2, who had medium-sized hematomas, exhibited challenges with verbal learning, verbal memory, word finding, and word generation. In contrast, Case 3, who had a small-sized hematoma, showed broadly preserved verbal abilities. All three cases exhibited challenges on at least one measure of executive functioning. The distinct performance of the three cases highlights the complexity of predicting neurocognitive abilities following childhood left hemisphere hemorrhagic stroke. The finding that all cases exhibited executive functioning deficits suggests an area of vulnerability in this population. Clinical implications include the importance of close monitoring and follow-up through comprehensive neuropsychological assessment in this population.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.195
Threshold uncertainty score0.799

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.282
Teacher spread0.268 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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