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Record W4409490483 · doi:10.1111/1758-2229.70083

Plasmid <scp>pPNptGreen</scp> Expression of Green Fluorescent Protein in <scp> <i>Pseudomonas chlororaphis</i> </scp> Strain <scp>S1Bt23</scp> Abrogates Biocontrol Activity Against <scp> <i>Pythium ultimum</i> </scp>

2025· article· en· W4409490483 on OpenAlexafffund
Mercy Akuma, Sylvia Ighem, Renlin Xu, Indira Thapa, Barbara A. Blackwell, James T. Tambong

Bibliographic record

VenueEnvironmental Microbiology Reports · 2025
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicPlant-Microbe Interactions and Immunity
Canadian institutionsUniversity of ManitobaCanadian Blood ServicesUniversity of OttawaAgriculture and Agri-Food Canada
FundersAgriculture and Agri-Food Canada
KeywordsPseudomonas chlororaphisGreen fluorescent proteinPythium ultimumBiologyMicrobiologyPlasmidInoculationMolecular biologyPseudomonasBotanyRhizoctonia solaniBacteriaBiochemistryGeneHorticulture

Abstract

fetched live from OpenAlex

Pseudomonas chlororaphis is a highly effective plant root coloniser and biocontrol agent. To monitor the colonisation of tomato and canola roots, P. chlororaphis S1Bt23 was transformed with the pPNptGreen plasmid encoding for green fluorescent protein (S1Bt23-GFP). Seedling roots inoculated with S1Bt23-GFP were examined after 2 and 5 h using confocal laser fluorescence microscopy. Roots exposed to S1Bt23-GFP showed pronounced biofilm formation around the root surface, and fluorescing cells were localised in the epidermis and metaxylem after 2 and 5 h of inoculation, respectively. The canola roots also showed upward active translocation of the S1Bt23-GFP cells in xylem vessels in real time. S1Bt23-GFP was also evaluated for antagonistic activity against Pythium ultimum. While S1Bt23 WT exhibited 65.70%-71.4% inhibition of radial growth of Py. ultimum, the S1Bt23-GFP strain did not demonstrate any antagonistic effects. Thin layer chromatography and liquid chromatography mass spectrometry analyses of culture extracts of S1Bt23-GFP did not detect phenazines or pyrrolnitrin, antifungal metabolites identified in S1Bt23 wild type. Expressions of phenazine and pyrrolnitrin genes showed no differences in S1Bt23-GFP and wild type. This suggests that the abrogation of these metabolites occurred post-transcriptionally, probably due to a high cellular molecular load in GFP production. This could negatively impact the ecological fitness of S1Bt23-GFP.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.107
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0000.001
Science and technology studies0.0010.001
Scholarly communication0.0000.001
Open science0.0010.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.191
Teacher spread0.185 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes2
Has abstractyes

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