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Record W4409508147 · doi:10.1038/s41598-025-96658-4

Fish consumption and gastric cancer within the Stomach cancer Pooling (StoP) Project

2025· review· en· W4409508147 on OpenAlexaff
Carlotta Franchi, Ilaria Ardoino, Sara Mandelli, Linia Patel, Claudio Pelucchi, Rossella Bonzi, M. Constanza Camargo, Charles S. Rabkin, Linda M. Liao, Rashmi Sinha, Kenneth C. Johnson, Jinfu Hu, Zuo‐Feng Zhang, Domenico Palli, Monica Ferraroni, Eva Negri, Federica Turati, Guo‐Pei Yu, Nuno Lunet, Samantha Morais, Lizbeth López‐Carrillo, Shoichiro Tsugane, Akihisa Hidaka, Reza Malekzadeh, Давид Заридзе, Dmitry Maximovitch, Jesús Vioqué, Sandra González‐Palacios, Mary H. Ward, Núria Aragonés, Gemma Castaño‐Vinyals, María Paula Curado, Emmanuel Dias‐Neto, Gerson Shigueaki Hamada, Raúl Ulises Hernández‐Ramírez, Mohammadreza Pakseresht, Farhad Pourfarzi, Lina Mu, Areti Lagiou, Παγώνα Λάγιου, Malaquías López‐Cervantes, Alberto Dolci, Stefania Boccia, Roberta Pastorino, Paolo Boffetta, Barbara D’Avanzo, Carlo La Vecchia

Bibliographic record

VenueScientific Reports · 2025
Typereview
Languageen
FieldMedicine
TopicNutritional Studies and Diet
Canadian institutionsUniversity of AlbertaOttawa Public HealthUniversity of Ottawa
FundersNational Cancer InstituteEuropean Regional Development FundFundação de Amparo à Pesquisa do Estado de São PauloFundação para a Ciência e a TecnologiaAssociazione Italiana per la Ricerca sul CancroUniversidade do PortoMinistero dell’Istruzione, dell’Università e della Ricerca
KeywordsFish <Actinopterygii>PoolingStomachCancerStomach cancerFisheryConsumption (sociology)MedicineBiologyInternal medicineComputer scienceArtificial intelligenceArt

Abstract

fetched live from OpenAlex

Gastric cancer is among the most common cancer and cause of cancer death. We conducted a meta-analysis of 25 case-control studies from the Stomach cancer Pooling Project to assess the association between fish or canned fish consumption and the risk of gastric cancer. 10,431 cases and 24,903 controls were available. We found no association between fish consumption and risk of gastric cancer (pooled odds ratios (OR) = 0.99; 95% confidence interval (CI) 0.86-1.13, for at least one serving/week vs none). Geographical differences were found: in Asia an increased intake of fish was associated with a lower stomach cancer risk. In the sensitivity analyses, fish consumption was associated to a lower risk of gastric cancer in models adjusted for family history of gastric cancer (OR = 0.80, 95% CI 0.72-0.89) and Helicobacter Pylori infection (OR = 0.72, 95% CI 0.60-0.88), but not for body mass index or energy intake. Seven studies collected information on canned fish (4525 cases and 8073 controls). No association was found for canned fish (OR = 0.96, 95% CI 0.82-1.13). In conclusion, our results provide evidence that fish and canned fish intake are not associated with gastric cancer risk, although geographical differences have been highlighted, with a lower risk of gastric cancer in Asia.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.019
metaresearch head score (Gemma)0.032
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.019
Threshold uncertainty score0.102

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0190.032
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0060.020
Bibliometrics0.0030.005
Science and technology studies0.0010.000
Scholarly communication0.0020.001
Open science0.0010.002
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.070
GPT teacher head0.390
Teacher spread0.320 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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