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Record W4409537933 · doi:10.1089/neu.2024.0483

Mechanism of Injury and Clinical Recovery Outcomes Following Pediatric Concussion

2025· article· en· W4409537933 on OpenAlexaff
Anastasiya Gudymenko, Sara Iuliano, Isabelle Gagnon, Grant L. Iverson, Nathan E. Cook, Roger Zemek, Elizabeth F. Teel

Bibliographic record

VenueJournal of Neurotrauma · 2025
Typearticle
Languageen
FieldMedicine
TopicTraumatic Brain Injury Research
Canadian institutionsUniversity of OttawaChildren's Hospital of Eastern OntarioMcGill UniversityMontreal Children's HospitalMcGill University Health CentreConcordia University
Fundersnot available
KeywordsConcussionTraumatic brain injuryMedicineMechanism (biology)Physical medicine and rehabilitationPoison controlInjury preventionIntensive care medicineEmergency medicinePsychiatry

Abstract

fetched live from OpenAlex

Children with concussion are injured through a variety of mechanisms, but the relationship between mechanism of injury (MOI) and recovery outcomes is unclear due to small sample sizes and varied methodological designs. Our objective was to examine the association of MOI and clinical recovery in youth with concussion using a large dataset collated from a single, multisite study. We hypothesized that sport-related concussion would be related to better clinical presentation and faster recovery trajectories compared to other mechanisms of concussion. This study was a secondary analysis of data collected during the Predicting and Preventing Postconcussive Problems in Pediatrics study. Children and adolescents with concussion ( n = 3056) completed the Child Sport Concussion Assessment Tool 3rd Edition and Postconcussion Symptom Inventory (PCSI) within 48 h following injury. Follow-up sessions at 1-, 2-, 4-, 8-, and 12-weeks post injury were completed using the PCSI and Pediatric Quality of Life Scale (PedsQL) scales. Acute clinical outcomes were analyzed using analysis of variances or chi-square analyses, while recovery trajectories were evaluated using linear and logistic regression. No MOI-based differences in acute clinical presentation were observed, except for balance outcomes in 13–17 year old ( F [2,1001] = 5.69, p = 0.003). Symptoms improved over time regardless of age ( p < 0.05). In 8–12 and 3–17 year olds, quality of life improved over time and was significantly higher in the sports group ( p < 0.05). The “other” mechanism group had higher odds of persistent symptoms at 4-week than the sports group in 8–12 year olds (OR = 2.01, 95% CI = 1.20, 3.40, p = 0.008), while this finding was reversed in the 13–17 group (OR = 0.61, 95% CI = 0.38, 0.99, p = 0.045). Sport-related concussions were generally associated with better symptom and quality of life scores in older children, but these differences were modest and unlikely to be clinically significant. Regardless of MOI, most children experienced clinical improvements across the first three months following concussion.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.006
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.006
Threshold uncertainty score0.012

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.006
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.117
GPT teacher head0.441
Teacher spread0.324 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes1
Has abstractyes

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