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Fluoroless Mapping and Ablation with Integration of a Pentaspline Pulsed Field Catheter

2025· preprint· en· W4409540995 on OpenAlexaff
Ayesha Shaik, Tri Q. Nguyen, Gregory F. Michaud, Alan Hanley

Bibliographic record

Venuenot available
Typepreprint
Languageen
FieldMaterials Science
TopicDiamond and Carbon-based Materials Research
Canadian institutionsAbbott (Canada)
Fundersnot available
KeywordsAblationField (mathematics)Catheter ablationCatheterBiomedical engineeringComputer scienceMaterials scienceMedicineRadiologyInternal medicineMathematics

Abstract

fetched live from OpenAlex

Introduction: Fluoroless mapping and ablation using Pentaspline pulsed field ablation catheter has many advantages. This can be achieved using “tripolar configuration” which enables high-quality electroanatomical maps, improved ability to localize EGMs, minimize use of additional mapping catheter when compared to the standard bipole configuration. We aimed to evaluate the benefits of using tripolar configuration in fluoroless atrial fibrillation ablation when compared to the standard bipolar configuration. Methods: The study was approved by the local Institutional Review Board. This study aims to compare a standard method of pinning the pentaspline catheter to an alternative “tripolar pinning” technique. In the tripolar pinning configuration, visualization of not only the 3rd electrode but also the “interpolation of electrode 1, 2, & 4 on each spline is done. Procedures were performed under general anesthesia, EnsiteX system (Abbott, Abbott Park, IL) was used for mapping. Intracardiac echo and electroanatomical map was used to identify catheter location and identify local EGMs. Tripole and standard bipole signals were displayed on the same page to evaluate the signals pre and post each PFA application. Results: Ablation was performed in 59 cases (42 males, average age 65 (30 – 85); 17 females, average age 74 (59 – 83)) in which we configured the catheter in tripole for comparison with the standard bipole setup. Geometry and post voltage maps were created using the tripolar signals in 40 of the 59 patients. Average case duration was 85 minutes (53 – 198; PVI alone 70 minutes (53 – 97)). The average number of PFA applications was 48 (31 – 72). Standard bipole EGMs demonstrated a large far field component when compared to tripole configuration. Ectopic atrial foci, atrial flutters were successfully mapped and ablated in four and five patients respectively. We were able to demonstrate line of block across mitral isthmus and cavotricuspid isthmus ablation. In cases where mapping was performed, geometry creation with the tripoles allowed for field scaling on Ensite X. Conclusion: Integration of the pentaspline pulsed field ablation catheter with the tripolar configuration is feasible and facilitates fluoroless PVI.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.021
Threshold uncertainty score0.546

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.282
Teacher spread0.262 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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